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本文引用的文献

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The impact of the COVID-19 pandemic on patterns of attendance at emergency departments in two large London hospitals: an observational study.COVID-19 大流行对两家伦敦大医院急诊科就诊模式的影响:一项观察性研究。
BMC Health Serv Res. 2021 Sep 23;21(1):1008. doi: 10.1186/s12913-021-07008-9.
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The impact of the COVID-19 pandemic on the presentation status of newly diagnosed melanoma: A single institution experience.2019年冠状病毒病大流行对新诊断黑色素瘤呈现状态的影响:单机构经验
J Am Acad Dermatol. 2021 Apr;84(4):1096-1098. doi: 10.1016/j.jaad.2020.12.034. Epub 2020 Dec 25.
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Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care.COVID-19 大流行对心血管门诊医疗模式的影响。
Am Heart J. 2021 Jan;231:1-5. doi: 10.1016/j.ahj.2020.10.074. Epub 2020 Nov 1.
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Change in obstetric attendance and activities during the COVID-19 pandemic.2019冠状病毒病大流行期间产科就诊及活动的变化。
Lancet Infect Dis. 2021 May;21(5):e115. doi: 10.1016/S1473-3099(20)30779-9. Epub 2020 Oct 5.
5
Impact of COVID-19 on outpatient visits and intravitreal treatments in a referral retina unit: let's be ready for a plausible "rebound effect".COVID-19 对转诊视网膜科门诊就诊和玻璃体内治疗的影响:让我们为可能出现的“反弹效应”做好准备。
Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2655-2660. doi: 10.1007/s00417-020-04858-7. Epub 2020 Sep 22.
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Disease and healthcare burden of COVID-19 in the United States.美国 COVID-19 疾病和医疗负担。
Nat Med. 2020 Aug;26(8):1212-1217. doi: 10.1038/s41591-020-0952-y. Epub 2020 Jun 16.
7
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
8
Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual.黑色素瘤分期:美国癌症联合委员会第八版癌症分期手册中基于证据的变化。
CA Cancer J Clin. 2017 Nov;67(6):472-492. doi: 10.3322/caac.21409. Epub 2017 Oct 13.
9
Frequency of excisions and yields of malignant skin tumors in a population-based screening intervention of 360,288 whole-body examinations.在一项基于人群的、包含360288次全身检查的筛查干预中,恶性皮肤肿瘤的切除频率及产出情况。
Arch Dermatol. 2012 Aug;148(8):903-10. doi: 10.1001/archdermatol.2012.893.
10
Systematic skin cancer screening in Northern Germany.在德国北部进行系统性皮肤癌筛查。
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隐藏在明处的危险:(另一个)新冠病毒的危险。

Hidden in plain sight: the (other) danger of COVID-19.

机构信息

Department of Plastic and Reconstructive Surgery, Rambam Health Care Campus, Haifa.

Bruce and Ruth Rappaport Faculty of Medicine, Technion.

出版信息

Melanoma Res. 2021 Aug 1;31(4):389-392. doi: 10.1097/CMR.0000000000000745.

DOI:10.1097/CMR.0000000000000745
PMID:33965975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8253375/
Abstract

The Novel Coronavirus disease (COVID-19) first emerged in Wuhan province, China, in late November 2019 and changed public healthcare perception. It has caused a significant decline in attendance to outpatient clinics. However, other diseases have not stopped, including malignant melanoma. Survey of the number of visits to plastic surgery outpatient clinic during the first lockdown in Israel concerning malignant melanoma was compared to the same months in the previous years. We assessed the number of visits to the oncology department during 2020 compared to the number of visits and treatment protocols for malignant melanoma. During the first lockdown, the attendance at the plastic surgery outpatient clinic and ambulatory surgery decreased significantly (P = 0.002), both in excisions of suspected malignant melanoma and malignant melanoma follow-ups (P = 0.019 and P = 0.035, respectively). The last third of 2020 (from September to December) had shown a significant rise in new protocols commenced (P < 0.001). This rise in the final third of the year was not noted in 2018 or 2019. These data clearly show the rise in advanced and metastatic malignant melanoma cases due to refraining from medical follow-ups and treatments during the COVID-19 pandemic. Diseases other than COVID-19 have not vanished, and continue to treat those diseases. Ignoring malignant melanoma treatment because of COVID-19 and vice-versa will not benefit our patients.

摘要

新型冠状病毒病(COVID-19)于 2019 年 11 月下旬在中国湖北省首次出现,改变了公众对医疗保健的看法。它导致门诊就诊人数显著下降。然而,其他疾病并未停止,包括恶性黑色素瘤。对以色列首次封锁期间整形外科门诊就诊恶性黑色素瘤的数量进行了调查,并与前几年同期进行了比较。我们评估了 2020 年与恶性黑色素瘤就诊和治疗方案相比,肿瘤科就诊的次数。在第一次封锁期间,整形外科门诊和日间手术就诊人数明显减少(P=0.002),疑似恶性黑色素瘤切除和恶性黑色素瘤随访的就诊人数均减少(P=0.019 和 P=0.035)。2020 年最后三分之一(从 9 月到 12 月)开始的新方案数量显著增加(P<0.001)。这种在年底三分之一的上升趋势在 2018 年或 2019 年并未出现。这些数据清楚地表明,由于 COVID-19 大流行期间推迟了医疗随访和治疗,晚期和转移性恶性黑色素瘤病例有所增加。COVID-19 以外的其他疾病并未消失,仍在治疗这些疾病。由于 COVID-19 而忽视恶性黑色素瘤的治疗,反之亦然,都不会使我们的患者受益。