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Effect of promethazine on the metabolism of chloroquine.

作者信息

Ehiemua A O, Komolafe O O, Oyedeji G A, Olamijulo S K

机构信息

University of Ife, Ile-Ife, Nigeria.

出版信息

Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):15-7. doi: 10.1007/BF03189922.

DOI:10.1007/BF03189922
PMID:3396608
Abstract

Co-administration of promethazine hydrochloride and chloroquine phosphate resulted in increased blood levels of chloroquine and its metabolites. However, there is no statistical difference between the means obtained for the initial rate of excretion and the total drug excreted within three hours.

摘要

相似文献

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Effect of promethazine on the metabolism of chloroquine.
Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):15-7. doi: 10.1007/BF03189922.
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Effect of promethazine on the metabolism of chloroquine.异丙嗪对氯喹代谢的影响。
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Residual chloroquine and metabolites in man as a sequel of previous chloroquine medications: a urinary excretion study and its significance.既往使用氯喹药物后人体中的残留氯喹及其代谢产物:一项尿排泄研究及其意义
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Absorption, distribution and excretion of 14C-chloroquine after single oral administration in albino and pigmented rats: binding characteristics of chloroquine-related radioactivity to melanin in-vivo.白化病大鼠和有色大鼠单次口服给药后14C-氯喹的吸收、分布和排泄:氯喹相关放射性在体内与黑色素的结合特性
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Prolonged kidney allograft survival with promethazine.异丙嗪延长肾移植存活时间
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Study of interactions between ibuprofen and sulfonamides, and between bucolome and sulfonamides in rats.布洛芬与磺胺类药物之间以及布可隆与磺胺类药物在大鼠体内的相互作用研究。
Chem Pharm Bull (Tokyo). 1985 Aug;33(8):3415-21. doi: 10.1248/cpb.33.3415.
2
Chloroquine resistance in malaria: variations of substrate-stimulated chloroquine accumulation.疟疾中的氯喹耐药性:底物刺激的氯喹蓄积变化
J Pharmacol Exp Ther. 1975 Dec;195(3):389-96.
3
Competitive binding between cocaine and various drugs to synthetic levodopa melanin.可卡因与各种药物对合成左旋多巴黑色素的竞争性结合。
J Pharm Sci. 1977 Nov;66(11):1544-7. doi: 10.1002/jps.2600661110.