Maslar I A, Ansbacher R
Division of Reproductive Biology and Behavior, Oregon Regional Primate Research Center, Beaverton 97006.
Fertil Steril. 1988 Aug;50(2):250-4. doi: 10.1016/s0015-0282(16)60068-7.
The effect of short-term progesterone (P) treatment in vitro on decidual prolactin (dPRL) production by human endometrium was investigated. Cultures prepared from proliferative endometrium received medium containing P for 3 hours, 1 day, or 3 days. The culture medium was then changed daily for 7 to 14 days, and the amounts of dPRL in the spent medium were measured by radioimmunoassay. The results of these experiments indicated that even a short exposure to elevated concentrations of P is adequate to stimulate dPRL production and that the resulting pattern of dPRL production is determined by the duration of the P treatment.
研究了短期体外孕酮（P）处理对人子宫内膜蜕膜催乳素（dPRL）产生的影响。从增殖期子宫内膜制备的培养物接受含P的培养基3小时、1天或3天。然后每天更换培养基，持续7至14天，并用放射免疫测定法测量用过的培养基中dPRL的量。这些实验结果表明，即使短期暴露于升高浓度的P也足以刺激dPRL的产生，并且产生的dPRL产生模式由P处理的持续时间决定。
