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在稳态下,活性溶质通量是否能控制细胞体积?

May active solute flux control the cell volume in the steady state?

作者信息

Wierzchaczewski M

机构信息

Department of Biophysics, Academy of Medicine, Wrocław, Poland.

出版信息

Gen Physiol Biophys. 1988 Feb;7(1):59-71.

PMID:3396850
Abstract

The dynamics of a bioreactor with a variable volume and an active solute flux based on the thermodynamics of irreversible processes and stability analysis was studied. The active solute flux may control both the bioreactor volume and the hydrostatic pressure as well as the concentration of the solute inside the cell in the steady state. The range of the active solute flux is limited by amplitudes (j1(0), J2(0] of the active transport depending on the membrane transport parameters. The dynamic system is stable for j0 greater than jth0.

摘要

基于不可逆过程热力学和稳定性分析,研究了具有可变体积和活性溶质通量的生物反应器的动力学。活性溶质通量在稳态下可控制生物反应器体积、静水压力以及细胞内溶质浓度。活性溶质通量的范围受取决于膜传输参数的主动运输幅度(j1(0),J2(0])限制。对于大于jth0的j0,动态系统是稳定的。

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