Wesner Jeff S, Van Peursem Dan, Flores José D, Lio Yuhlong, Wesner Chelsea A
Department of Biology, University of South Dakota, Vermillion, SD 57069 USA.
Department of Mathematical Sciences, University of South Dakota, Vermillion, SD 57069 USA.
J Healthc Inform Res. 2021;5(2):218-229. doi: 10.1007/s41666-021-00094-8. Epub 2021 May 1.
Anticipating the number of hospital beds needed for patients with COVID-19 remains a challenge. Early efforts to predict hospital bed needs focused on deriving predictions from SIR models, largely at the level of countries, provinces, or states. In the USA, these models rely on data reported by state health agencies. However, predicting disease and hospitalization dynamics at the state level is complicated by geographic variation in disease parameters. In addition, it is difficult to make forecasts early in a pandemic due to minimal data. Bayesian approaches that allow models to be specified with informed prior information from areas that have already completed a disease curve can serve as prior estimates for areas that are beginning their curve. Here, a Bayesian non-linear regression (Weibull function) was used to forecast cumulative and active COVID-19 hospitalizations for SD, USA, based on data available up to 2020-07-22. As expected, early forecasts were dominated by prior information, which was derived from New York City. Importantly, hospitalization trends differed within South Dakota due to early peaks in an urban area, followed by later peaks in rural areas of the state. Combining these trends led to altered forecasts with relevant policy implications.
The online version contains supplementary material available at 10.1007/s41666-021-00094-8.
预测新型冠状病毒肺炎(COVID-19)患者所需的医院病床数量仍然是一项挑战。早期预测医院病床需求的努力主要集中在从SIR模型推导预测结果,大多是在国家、省份或州层面。在美国,这些模型依赖于州卫生机构报告的数据。然而,由于疾病参数的地理差异,在州层面预测疾病和住院动态情况较为复杂。此外,由于数据极少,在疫情早期很难进行预测。贝叶斯方法允许根据已完成疾病曲线的地区的先验信息来指定模型,可为刚开始出现曲线的地区提供先验估计。在此,基于截至2020年7月22日的可用数据,使用贝叶斯非线性回归(威布尔函数)来预测美国南达科他州COVID-19的累计住院人数和现患住院人数。正如预期的那样,早期预测主要受来自纽约市的先验信息主导。重要的是,南达科他州内部的住院趋势有所不同,因为该州城市地区出现了早期高峰,随后农村地区出现了后期高峰。综合这些趋势导致预测结果发生变化,具有相关的政策意义。
在线版本包含可在10.1007/s41666-021-00094-8获取的补充材料。