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几个世纪以来的大流行病。

Pandemics throughout the centuries.

作者信息

Schwartz Robert A, Kapila Rajendra

机构信息

Departments of Dermatology, Pathology, and Pediatrics, Rutgers New Jersey Medical School, Infectious Diseases, Newark, New Jersey, USA.

Departments of Dermatology, Pathology, and Pediatrics, Rutgers New Jersey Medical School, Infectious Diseases, Newark, New Jersey, USA.

出版信息

Clin Dermatol. 2021 Jan-Feb;39(1):5-8. doi: 10.1016/j.clindermatol.2020.12.006. Epub 2020 Dec 17.

DOI:10.1016/j.clindermatol.2020.12.006
PMID:33972052
Abstract

Pandemics have ravished the globe periodically, often associated with war, at times commencing as fever and rash, beginning in recorded history in the crowded walled city of Athens during the Peloponnesian War as described in great detail by the Athenian historian and military general Thucydides in 430 BCE. As the world now faces the first major pandemic of the 21st century, we focus on the "plague" commencing in Athens in 430 BCE and the 2 pandemics of the more recent century, which killed more than one million, the Spanish flu of 1918 and the Asian flu of 1957. The latter linked with successful vaccine development thanks to the heroic efforts of microbiologist Maurice Hilleman. We now look back and then forward to the viral infection coronavirus disease 2019 now devastating the world.

摘要

大流行病周期性地肆虐全球,常常与战争相关联,有时始于发热和皮疹,自有记录的历史以来,最早可追溯到伯罗奔尼撒战争期间雅典拥挤的城墙环绕的城市,雅典历史学家兼军事将领修昔底德在公元前430年对此有过详细描述。如今,世界正面临21世纪的首次重大大流行病,我们将重点关注公元前430年始于雅典的“瘟疫”以及近一个世纪以来的两次大流行病,它们造成了超过一百万人死亡,即1918年的西班牙流感和1957年的亚洲流感。由于微生物学家莫里斯·希勒曼的英勇努力,后者与成功研发疫苗有关。我们现在回顾过去,然后展望正在肆虐全球的2019冠状病毒病这一病毒感染。

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