Department of Obstetrics and Gynecology, Amsterdam University Medical Centers, University of Amsterdam, Room H4-205, PO Box 22660, Amsterdam 1105 AZ, The Netherlands.
Department of Obstetrics and Gynecology, Amsterdam University Medical Centers, University of Amsterdam, Room H4-205, PO Box 22660, Amsterdam 1105 AZ, The Netherlands; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Huispostcode CB20, Hanzeplein 1, Groningen 9700 RB, The Netherlands.
Obstet Gynecol Clin North Am. 2021 Jun;48(2):371-385. doi: 10.1016/j.ogc.2021.02.007.
Impaired fetal growth owing to placental insufficiency is a major contributor to adverse perinatal outcomes. No intervention is available that improves outcomes by changing the pathophysiologic process. Monitoring in early-onset fetal growth restriction (FGR) focuses on optimizing the timing of iatrogenic preterm delivery using cardiotocography and Doppler ultrasound. In late-onset FGR, identifying the fetus at risk for immediate hypoxia and who benefits from expedited delivery is challenging. It is likely that studies in the next decade will provide evidence how to best integrate different monitoring variables and other prognosticators in risk models that are aimed to optimize individual treatment strategies.
由于胎盘功能不全导致的胎儿生长受限是围产期不良结局的主要原因。目前尚无干预措施可以通过改变病理生理过程来改善结局。在胎儿生长受限（FGR）的早期监测中，重点是使用胎心监护和多普勒超声优化医源性早产的时机。在晚期 FGR 中，确定有立即缺氧风险并受益于加速分娩的胎儿具有挑战性。在未来十年，很可能会有研究提供证据，说明如何最好地整合不同的监测变量和其他预后因素，以优化旨在优化个体治疗策略的风险模型。
