CIMR, University of Cambridge, Cambridge, UK.
Universität Konstanz, Konstanz, Germany.
Nat Struct Mol Biol. 2021 May;28(5):404-408. doi: 10.1038/s41594-021-00593-7.
Structural biology plays a crucial role in the fight against COVID-19, permitting us to ‘see’ and understand SARS-CoV-2. However, the macromolecular structures of SARS-CoV-2 proteins that were solved with great speed and urgency can contain errors that may hinder drug design. The Coronavirus Structural Task Force has been working behind the scenes to evaluate and improve these structures, making the results freely available at https://insidecorona.net/.
结构生物学在抗击 COVID-19 方面发挥着至关重要的作用，使我们能够“看到”并了解 SARS-CoV-2。然而，以惊人的速度和紧迫性解决的 SARS-CoV-2 蛋白的大分子结构可能包含错误，从而阻碍药物设计。冠状病毒结构特别工作组一直在幕后努力评估和改进这些结构，并在 https://insidecorona.net/ 免费提供这些结果。
