McCombie N, Rock G
Ottawa Centre, Canadian Red Cross, Blood Transfusion Service.
J Clin Apher. 1988;4(2-3):104-7. doi: 10.1002/jca.2920040213.
Plasmapheresis is widely carried out to produce plasma for fractionation. Production of Factor VIII and albumin, two proteins in plasma, drives the plasma industry. The Canadian Red Cross would like to achieve national self-sufficiency in plasma production to meet the rising demands for these proteins in the next 4 years. In order to achieve this goal we must make efficient use of our automated plasmapheresis machines and available human resources to produce a cost-effective plasma product. An assessment was undertaken at the Ottawa Centre to evaluate the number of procedures which could be performed on each machine per day and the staff required to operate these machines safely and efficiently. Donor availability, reliability and reasons for donating plasma were recorded to determine if our population could support such an escalated programme. Donor/staff interest and acceptance of automated equipment was determined. The results showed that four automated plasmapheresis devices could be operated by one nurse and one clinic assistant processing 32 donors a day with an average time of 27 min required for a 500-ml donation of plasma. The donor population was available and extremely interested; however, the logistics of scheduling proved to be an area for concern requiring special attention.
进行血浆置换术以生产用于分离的血浆。血浆中的两种蛋白质——凝血因子VIII和白蛋白的生产推动了血浆产业的发展。加拿大红十字会希望在血浆生产方面实现全国自给自足，以满足未来4年对这些蛋白质不断增长的需求。为了实现这一目标，我们必须有效利用我们的自动血浆置换机和现有人力资源，以生产出具有成本效益的血浆产品。渥太华中心进行了一项评估，以评估每台机器每天可进行的操作程序数量以及安全高效操作这些机器所需的工作人员。记录了献血者的可获得性、可靠性以及献血浆的原因，以确定我们的人群是否能够支持这样一个扩大的项目。确定了献血者/工作人员对自动化设备的兴趣和接受程度。结果表明，一名护士和一名诊所助理可以操作四台自动血浆置换设备，每天处理32名献血者，采集500毫升血浆平均需要27分钟。有足够数量且非常感兴趣的献血者群体；然而，日程安排的后勤工作被证明是一个需要特别关注的令人担忧的领域。
