Department of Neurosciences, Philippine General Hospital, Manila, Philippines
Department of Neurosciences, Philippine General Hospital, Manila, Philippines.
BMJ Case Rep. 2021 May 11;14(5):e242365. doi: 10.1136/bcr-2021-242365.
The COVID-19 pandemic has led to a rise in cases of Guillain-Barré syndrome (GBS). This autoimmune sequela is a manifestation of the neurotropism potential of the virus. At present, knowledge regarding the pathophysiology, clinical features, management and outcomes of the condition is still evolving. This paper presents the case of a 22-year-old pregnant patient who came in with a history of upper respiratory tract symptoms followed by acroparaesthesia and progressive ascending weakness. She was confirmed to have COVID-19 and GBS and was subsequently managed with intravenous immunoglobulin (IVIg) followed by supportive therapy. To the authors' knowledge and based on their literature search, this is the first reported case of GBS in a COVID-19 confirmed pregnant patient who received IVIg.
新冠疫情导致吉兰-巴雷综合征（GBS）病例增加。这种自身免疫性后遗症是病毒神经亲嗜性的表现。目前，对于该病的病理生理学、临床特征、管理和预后的认识仍在不断发展。本文报告了一例 22 岁孕妇的病例，她因上呼吸道症状就诊，随后出现四肢感觉异常和进行性上升性无力。她被确诊为新冠病毒感染和 GBS，随后接受了静脉注射免疫球蛋白（IVIg）治疗和支持性治疗。据作者所知，并根据他们的文献检索，这是首例接受 IVIg 治疗的新冠确诊孕妇并发 GBS 的病例。
