Wang Jue, Bahabri Amin, Wong Patricia, Anantharachagan Arisudhan
Fiona Stanley Hospital, Australia.
Case Rep Womens Health. 2023 Mar 1;37:e00489. doi: 10.1016/j.crwh.2023.e00489. eCollection 2023 Mar.
Guillain-Barré syndrome (GBS) is an autoimmune neurological disorder with unknown aetiology. Given the incidence of GBS is between 1.2 and 1.9 cases per 100,000 people annually [1], it is extremely rare in pregnancy. We report a case with a challenging diagnosis of pre-eclampsia (PET) in a 34-year-old diabetic primigravida who was diagnosed with GBS at 30 weeks of gestation. At her initial presentation, she complained of progressive weakness of her limbs and facial muscles. This was associated with difficulty swallowing. The diagnosis of GBS was made based on electromyography (EMG) and clinical findings. She was managed conservatively with supportive management and was delivered by lower segment caesarean section at 34 weeks of gestation due to rapidly deteriorating liver function tests (LFTs) in the likely setting of PET.
吉兰-巴雷综合征（GBS）是一种病因不明的自身免疫性神经疾病。鉴于GBS的年发病率为每10万人中有1.2至1.9例[1]，在妊娠期极为罕见。我们报告一例34岁的糖尿病初产妇病例，该患者在妊娠30周时被诊断为GBS，其诊断为先兆子痫（PET）颇具挑战性。在其首次就诊时，她主诉四肢和面部肌肉进行性无力。这伴有吞咽困难。GBS的诊断基于肌电图（EMG）和临床检查结果。她接受了保守的支持性治疗，由于在可能为PET的情况下肝功能检查（LFTs）迅速恶化，于妊娠34周时行下段剖宫产分娩。
