Ankjaergaard O, Lawaetz K D, Andreassen U K
ENT Department, Hillerød County Hospital.
J Laryngol Otol. 1988 Jun;102(6):543-5. doi: 10.1017/s0022215100105614.
Atypical histiocytic granuloma in the oral mucosa has recently been described as a benign non-neoplastic ulcero-proliferative lesion of histiocytic origin with eosinophilia. The disease is confined to the oral mucosa where the lesion is solitary. These lesions, which heal spontaneously, are not associated with systemic disease or dissemination. This report deals with such a case, and it stresses the benign nature of the lesion despite the worrying clinical and microscopic appearance. The morphological diagnosis was substantiated by the use of a series of immunohistochemical reactions.
口腔黏膜非典型组织细胞性肉芽肿最近被描述为一种起源于组织细胞且伴有嗜酸性粒细胞增多的良性非肿瘤性溃疡增殖性病变。该疾病局限于口腔黏膜，病变为单发。这些病变可自行愈合，与全身性疾病或扩散无关。本报告涉及这样一个病例，并强调尽管病变在临床和显微镜下表现令人担忧，但其本质是良性的。通过一系列免疫组织化学反应证实了形态学诊断。
