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非典型组织细胞性肉芽肿。口腔一种不寻常的假性恶性反应性病变的光镜、超微结构及组织化学表现

Atypical histiocytic granuloma. Light microscopic, ultrastructural, and histochemical findings in an unusual pseudomalignant reactive lesion of the oral cavity.

作者信息

Eversole L R, Leider A S, Jacobsen P L, Kidd P M

出版信息

Cancer. 1985 Apr 15;55(8):1722-9. doi: 10.1002/1097-0142(19850415)55:8<1722::aid-cncr2820550818>3.0.co;2-h.

DOI:10.1002/1097-0142(19850415)55:8<1722::aid-cncr2820550818>3.0.co;2-h
PMID:3884130
Abstract

Four cases of an ulcero-proliferative lesion of putative histiocytic origin, arising in the oral cavity, are described. This lesion, which has not been defined previously, is easily confused histologically with a malignant process of lymphoid origin, thereby representing a pseudolymphomatous proliferation. Light microscopic, ultrastructural, and histochemical characteristics including immunoglobulin negativity, positive esterase reactivity, and positive peanut lectin binding support a histiocytic origin. These lesions are not associated with systemic disease or dissemination and heal spontaneously despite their worrisome microscopic appearance.

摘要

本文描述了4例起源于口腔、推测为组织细胞来源的溃疡增生性病变。这种病变以前未被明确界定,在组织学上很容易与淋巴来源的恶性病变相混淆,因此表现为假淋巴瘤性增生。光镜、超微结构及组织化学特征,包括免疫球蛋白阴性、酯酶反应阳性及花生凝集素结合阳性,均支持其组织细胞来源。这些病变与全身疾病或播散无关,尽管其镜下表现令人担忧,但可自发愈合。

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Atypical histiocytic granuloma. Light microscopic, ultrastructural, and histochemical findings in an unusual pseudomalignant reactive lesion of the oral cavity.非典型组织细胞性肉芽肿。口腔一种不寻常的假性恶性反应性病变的光镜、超微结构及组织化学表现
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