Yamaguchi Kei, Matsunuma Ryoichi, Hayami Ryosuke, Tsuneizumi Michiko
Department of Breast Surgery, Shizuoka Prefectural Hospital Organization, Shizuoka General Hospital, Shizuoka, Japan.
Case Rep Oncol. 2021 Mar 23;14(1):580-584. doi: 10.1159/000514980. eCollection 2021 Jan-Apr.
Advanced breast cancer with skin ulceration, bleeding, and odor is associated with impaired quality of life (QoL). In patients with metastatic breast cancer, treatment aims to relieve symptoms, improve QoL, and slow the progression of cancer. Occasionally, it is extremely difficult to alleviate symptoms and improve QoL in patients with breast cancer and skin ulceration, especially elderly patients. Since patient age, patient preferences, and the expected survival benefit from treatment are factors that influence the selection of therapy, physicians should provide an optimal treatment for patients with metastatic disease depending on the situation. In this study, we report the case of an elderly patient with metastatic breast cancer who had substantial skin ulceration. In this patient, multidisciplinary treatment including chemotherapy, radiotherapy, and surgery resulted in significantly improved QoL.
伴有皮肤溃疡、出血及异味的晚期乳腺癌与生活质量（QoL）受损相关。在转移性乳腺癌患者中，治疗旨在缓解症状、改善生活质量并减缓癌症进展。偶尔，对于患有乳腺癌及皮肤溃疡的患者，尤其是老年患者，缓解症状和改善生活质量极其困难。由于患者年龄、患者偏好以及治疗预期生存获益是影响治疗选择的因素，医生应根据具体情况为转移性疾病患者提供最佳治疗。在本研究中，我们报告了一例患有大量皮肤溃疡的老年转移性乳腺癌患者的病例。在该患者中，包括化疗、放疗及手术在内的多学科治疗使生活质量得到显著改善。
