Phan Hai Thanh, Tran Kiem Hao, Nguyen Huu Son
Department of Abdominal Emergency and Pediatric Surgery, Hue Central Hospital, Hue, Vietnam.
Pediatric Center, Hue Central Hospital, Hue, Vietnam.
Case Rep Neurol. 2021 Mar 19;13(1):184-189. doi: 10.1159/000512809. eCollection 2021 Jan-Apr.
Meningoencephalitis is not a rare disease in children. However, eosinophilic meningitis due to is unusual in the pediatric population. We describe the case of a 12-year-old girl from the central area of Vietnam with eosinophilic meningitis due to . The patient lived in a rural area, where farming is widespread, and presented with fever and headache. Laboratory results showed peripheral eosinophilia, a cerebrospinal fluid white blood cell count of 730/mm with 65% eosinophils. Cerebrospinal fluid ELISA was positive for , and blood ELISA was positive for . The presentation was consistent with a diagnosis of eosinophilic meningitis. The patient recovered fully after administration of albendazole (200 mg/day for 2 weeks), as well as intravenous dexamethasone (0.6 mg/kg/day every 8 h) and mannitol (1.5 g/kg/day every 8 h) for the first 3 days, followed by 5 days of oral prednisolone (2 mg/kg/day).
脑膜脑炎在儿童中并非罕见疾病。然而，由[未提及病因]引起的嗜酸性粒细胞性脑膜炎在儿科人群中并不常见。我们描述了一名来自越南中部地区的12岁女孩因[未提及病因]患嗜酸性粒细胞性脑膜炎的病例。该患者生活在农村地区，那里农业广泛，她出现发热和头痛症状。实验室结果显示外周血嗜酸性粒细胞增多，脑脊液白细胞计数为730/mm³，其中嗜酸性粒细胞占65%。脑脊液酶联免疫吸附测定（ELISA）检测[未提及病原体]呈阳性，血液ELISA检测[未提及病原体]呈阳性。临床表现符合[未提及病原体]嗜酸性粒细胞性脑膜炎的诊断。患者在服用阿苯达唑（200毫克/天，共2周）以及静脉注射地塞米松（0.6毫克/千克/天，每8小时一次）和甘露醇（1.5克/千克/天，每8小时一次）治疗的前3天，随后口服泼尼松龙（2毫克/千克/天）5天后完全康复。
