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一名干洗工人因职业接触溶剂而患类脂性肺炎的病例。

A case of lipoid pneumonia associated with occupational exposure to solvents in a dry-cleaning worker.

作者信息

Park Sunji, Park Ji Eun, Lee Jaehee

机构信息

Department of Internal Medicine Kyungpook National University, School of Medicine Daegu Republic of Korea.

出版信息

Respirol Case Rep. 2021 May 7;9(6):e00762. doi: 10.1002/rcr2.762. eCollection 2021 Jun.

DOI:10.1002/rcr2.762
PMID:33976891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8103084/
Abstract

Lipoid pneumonia can develop from exposure to different types of oil, but occupational exposure is rare. A 58-year-old woman was referred to our hospital for patchy airspace opacities in the lungs with lower lobe predominance on chest computed tomography. She was diagnosed with non-Hodgkin's lymphoma seven years ago, but was in complete remission. She had mild cough and sputum, but no history of taking any lipid-containing agents. The bronchoalveolar lavage fluid revealed lipid-laden macrophages with Oil Red O staining, which led to the suspicion of lipoid pneumonia. Re-evaluation of her personal history revealed that she was a dry-cleaning worker who worked with organic solvent sprayers. Her condition was successfully managed with corticosteroids and avoidance of further occupational exposure to the substance. This rare case of occupational exogenous lipoid pneumonia in a dry-cleaning worker suggests the importance of considering a patient's occupational history during diagnosis.

摘要

类脂性肺炎可因接触不同类型的油类而发生,但职业暴露很少见。一名58岁女性因胸部计算机断层扫描显示肺部有斑片状气腔实变且以下叶为主,被转诊至我院。她七年前被诊断为非霍奇金淋巴瘤,但已完全缓解。她有轻度咳嗽和咳痰,但无服用任何含脂质药物的病史。支气管肺泡灌洗液经油红O染色显示有充满脂质的巨噬细胞,这引发了类脂性肺炎的怀疑。重新评估她的个人史发现,她是一名干洗工人,曾使用有机溶剂喷雾器。她的病情通过使用皮质类固醇并避免进一步职业接触该物质而得到成功控制。这名干洗工人发生职业性外源性类脂性肺炎的罕见病例表明,在诊断过程中考虑患者职业史的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d68/8103084/31b884e19f90/RCR2-9-e00762-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d68/8103084/31b884e19f90/RCR2-9-e00762-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d68/8103084/31b884e19f90/RCR2-9-e00762-g001.jpg

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引用本文的文献

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Bronchoalveolar Lavages Combined With Glucocorticoids in Management of Acute Exogenous Lipoid Pneumonia: 3 Case Reports.支气管肺泡灌洗联合糖皮质激素治疗急性外源性类脂性肺炎:3例病例报告
Case Rep Med. 2025 Aug 30;2025:4165969. doi: 10.1155/carm/4165969. eCollection 2025.
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Polyinfection secondary to exogenous lipoid pneumonia caused by aspiration of paraffin oil: a Case Report.石蜡油误吸所致外源性类脂性肺炎继发多重感染:病例报告
Front Med (Lausanne). 2025 Aug 1;12:1555471. doi: 10.3389/fmed.2025.1555471. eCollection 2025.
3
[Not Available].

本文引用的文献

1
Occupational and work-related respiratory disease attributed to cleaning products.因清洁产品导致的职业性和与工作相关的呼吸道疾病。
Occup Environ Med. 2019 Aug;76(8):530-536. doi: 10.1136/oemed-2018-105646. Epub 2019 Jun 5.
2
Investigation of rare chronic lipoid pneumonia associated with occupational exposure to paraffin aerosol.与职业性接触石蜡气雾剂相关的罕见慢性类脂质性肺炎的调查。
J Occup Health. 2016 Sep 30;58(5):482-488. doi: 10.1539/joh.16-0096-CS. Epub 2016 Aug 4.
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外源性类脂性肺炎。临床和放射学表现。
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