Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081, LA, Amsterdam, The Netherlands.
Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Clin Oral Investig. 2021 Dec;25(12):6661-6669. doi: 10.1007/s00784-021-03952-2. Epub 2021 May 12.
Medical professionals should advise their patients to visit a dentist if necessary. Due to the lack of time and knowledge, screening for periodontitis is often not done. To alleviate this problem, a screening model for total (own teeth/gum health, gum treatment, loose teeth, mouthwash use, and age)/severe periodontitis (gum treatment, loose teeth, tooth appearance, mouthwash use, age, and sex) in a medical care setting was developed in the Academic Center of Dentistry Amsterdam (ACTA) [1]. The purpose of the present study was to externally validate this tool in an outpatient medical setting.
Patients were requited in an outpatient medical setting as the validation cohort. The self-reported oral health questionnaire was conducted, demographic data were collected, and periodontal examination was performed. Algorithm discrimination was expressed as the area under the receiver operating characteristic curve (AUROCC). Sensitivity, specificity, and positive and negative predictive values were calculated. Calibration plots were made.
For predicting total periodontitis, the AUROCC was 0.59 with a sensitivity of 49% and specificity of 68%. The PPV was 57% and the NPV scored 55%. For predicting severe periodontitis, the AUROCC was 0.73 with a sensitivity of 71% and specificity of 63%. The PPV was 39% and the NPV 87%.
The performance of the algorithm for severe periodontitis is found to be sufficient in the current medical study population. Further external validation of periodontitis algorithms in non-dental school populations is recommended.
Because general physicians are obligated to screen patients for periodontitis, it is our general goal that they can use a prediction model in medical settings without an oral examination.
医疗专业人员应建议其患者必要时去看牙医。由于缺乏时间和知识,牙周炎的筛查往往无法进行。为了解决这个问题,在阿姆斯特丹牙科学术中心(ACTA)[1]开发了一种针对医疗保健环境中的总(自己的牙齿/牙龈健康、牙龈治疗、松动牙齿、使用漱口水和年龄)/严重牙周炎(牙龈治疗、松动牙齿、牙齿外观、使用漱口水、年龄和性别)的筛查模型。本研究的目的是在门诊医疗环境中对外科验证该工具。
在门诊医疗环境中需要患者作为验证队列。进行了自我报告的口腔健康问卷,收集了人口统计学数据,并进行了牙周检查。算法区分度表示为接收器工作特征曲线(AUROCC)下的面积。计算了灵敏度、特异性、阳性和阴性预测值。制作了校准图。
对于预测总牙周炎,AUROCC 为 0.59,灵敏度为 49%,特异性为 68%。PPV 为 57%,NPV 为 55%。对于预测严重牙周炎,AUROCC 为 0.73,灵敏度为 71%,特异性为 63%。PPV 为 39%,NPV 为 87%。
在当前的医学研究人群中,严重牙周炎算法的性能被认为是足够的。建议在非牙科学校人群中进一步验证牙周炎算法。
由于普通医生有义务对牙周炎患者进行筛查,因此我们的总体目标是让他们能够在没有口腔检查的情况下在医疗环境中使用预测模型。