Li Mozhu, Haque Waqas, Vuppala Suchith, Tobias Ethan
Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA
Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
BMJ Case Rep. 2021 May 12;14(5):e242392. doi: 10.1136/bcr-2021-242392.
Multisystem inflammatory syndrome in adults (MIS-A) is a rare but often severe complication of SARS-CoV-2 infection. While several case reports about MIS-A in the setting of COVID-19 have been published since the term was first coined in June 2020, a clear description of the underlying pathophysiology and guideline-based recommendations on the diagnostic and therapeutic approach are lacking. What has been reported is that in the absence of severe respiratory illness, MIS-A can present with hypotension or shock, high-grade fever, abdominal pain, diarrhoea and severe weakness days to weeks after SARS-CoV-2 infection. Here, we present a case of a 28-year-old man who presented with a rarely described initial symptom: unilateral neck swelling. His presentation, disease progression and treatment course provide further information about MIS-A as a complication and in formulating diagnostic guidelines.
成人多系统炎症综合征（MIS-A）是一种由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染引发的罕见但通常较为严重的并发症。自2020年6月首次提出“成人多系统炎症综合征”这一术语以来，已有多篇关于新型冠状病毒肺炎（COVID-19）背景下成人多系统炎症综合征的病例报告发表，但对于其潜在病理生理学的清晰描述以及基于指南的诊断和治疗方法建议仍较为缺乏。据报道，在没有严重呼吸道疾病的情况下，成人多系统炎症综合征可在SARS-CoV-2感染后的数天至数周内出现低血压或休克、高热、腹痛、腹泻和严重虚弱等症状。在此，我们报告一例28岁男性患者，其最初症状为罕见的单侧颈部肿胀。他的临床表现、疾病进展和治疗过程为成人多系统炎症综合征作为一种并发症以及制定诊断指南提供了更多信息。
