Ladi-Seyedian Seyedeh-Sanam, Sharifi-Rad Lida, Alimadadi Hosein, Nabavizadeh Behnam, Manouchehri Navid, Allahverdi Bahar, Motamed Farzaneh, Fallahi Gholam-Hossein
Pediatric Gastroenterology and Hepatology Research Center, Pediatric Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, No. 62, Dr. Qarib St, Keshavarz Blvd, 14194 33151, Tehran, Iran.
Pelvic Floor Rehabilitation and Urotherapy Group (PFRUG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Dig Dis Sci. 2022 Mar;67(3):989-996. doi: 10.1007/s10620-021-07012-3. Epub 2021 May 12.
We compared the effects of transcutaneous functional electrical stimulation (TFES) and biofeedback therapy with TFES alone in a cohort of children with functional non-retentive fecal incontinence (FNRFI).
This prospective, single-center randomized clinical trial was performed on 40 children with FNRFI. Patients were randomly allocated into two equal treatment groups. Group A (n = 20) underwent TFES + biofeedback therapy, and group B (n = 20) received TFES alone. All patients were assessed with a pediatric fecal incontinence (FI) score questionnaire, a visual pain score, and a bowel habit diary both before and at the end of treatment sessions and also at 6 months of follow-up. In addition, a FI quality-of-life (QoL) questionnaire was recorded for all patients before and 6 months after the treatment.
FI significantly improved in 13/20 (65%) patients in group A and 11/20 (55%) patients in group B (P < 0.05). A significant reduction in FI score was seen in each group at the end of treatment sessions and maintained at 6 months of follow-up (P < 0.05). A significant improvement in FI-QoL scores was seen in both groups at 6 months of follow-up in which there was no significant difference in terms of FI-QoL scores improvement between both groups after treatment.
The use of electrical stimulation in combination with other treatment methods improves symptoms in patients with FNRFI who are refractory to conventional treatment.
我们比较了经皮功能性电刺激（TFES）和单纯TFES生物反馈疗法对一组功能性非潴留性大便失禁（FNRFI）儿童的影响。
对40例FNRFI儿童进行了这项前瞻性、单中心随机临床试验。患者被随机分为两个相等的治疗组。A组（n = 20）接受TFES + 生物反馈疗法，B组（n = 20）仅接受TFES。所有患者在治疗前、治疗结束时以及随访6个月时均通过小儿大便失禁（FI）评分问卷、视觉疼痛评分和排便习惯日记进行评估。此外，在治疗前和治疗后6个月为所有患者记录FI生活质量（QoL）问卷。
A组13/20（65%）患者和B组11/20（55%）患者的FI有显著改善（P < 0.05）。每组在治疗结束时FI评分均显著降低，并在随访6个月时维持（P < 0.05）。两组在随访6个月时FI-QoL评分均有显著改善，治疗后两组在FI-QoL评分改善方面无显著差异。
电刺激与其他治疗方法联合使用可改善对传统治疗难治的FNRFI患者的症状。
