Department of Medical Oncology, Canakkale Onsekiz Mart University Faculty of Medicine, Canakkale, Turkey.
Psychooncology. 2021 Oct;30(10):1765-1772. doi: 10.1002/pon.5727. Epub 2021 Jun 9.
This study examines the relationships between fear of cancer recurrence (FCR), spiritual well-being (SWB) and psychological resilience in breast cancer survivors during the COVID-19 outbreak, and investigates to what extent breast cancer survivors' sociodemographic characteristics affect FCR, SWB and psychological resilience levels.
The study was conducted at Canakkale University Hospital in Turkey. Included in the study were 82 non-metastatic breast cancer patients whose clinical outcomes were followed-up after primary treatment, but suspended due to the COVID-19 outbreak. FCR, SWB and psychological resilience were assessed using the FCR inventory-short form (FCRI-SF), SWB scale and the brief resilience scale (BRS), respectively.
The mean scores of breast cancer survivors concerning FCR, SWB, and psychological resilience were 17.77 ± 5.38, 36.20 ± 6.21 and 20.01 ± 4.51, respectively. A significant negative correlation was noted between the scores of FCR and SWB and psychological resilience (r = -0.329, p < 0.001 and r = -0.316, p = 0.004, respectively). Additionally, a significantly positive correlation was identified between psychological resilience and SWB (r = 0.501, p = 0.003). A hierarchical linear regression analysis with FCRI-SF as the dependent variable, and SWB and BRS as explanatory variables, indicated that SWB affects FCRI-SF scores and is a potential predictor of FCR. A mediation analysis revealed that SWB partially mediated the relationship between psychological resilience and FCR.
Breast cancer survivors with high SWB and psychological resilience scores experience less FCR, despite their failure to maintain the medical follow-up due to the COVID-19 outbreak. Efforts should be made to increase the psychological resilience and SWB of patients diagnosed with breast cancer.
本研究考察了 COVID-19 大流行期间乳腺癌幸存者中癌症复发恐惧（FCR）、精神幸福感（SWB）和心理弹性之间的关系，并探讨了乳腺癌幸存者的社会人口统计学特征在多大程度上影响 FCR、SWB 和心理弹性水平。
该研究在土耳其的恰纳卡莱大学医院进行。纳入研究的是 82 名非转移性乳腺癌患者，他们在接受初级治疗后进行了临床随访，但由于 COVID-19 大流行而暂停。使用 FCR 清单短表（FCRI-SF）、SWB 量表和简短韧性量表（BRS）分别评估 FCR、SWB 和心理弹性。
乳腺癌幸存者的 FCR、SWB 和心理弹性平均得分分别为 17.77±5.38、36.20±6.21 和 20.01±4.51。FCR 得分与 SWB 和心理弹性呈显著负相关（r=-0.329，p<0.001 和 r=-0.316，p=0.004）。此外，心理弹性与 SWB 呈显著正相关（r=0.501，p=0.003）。以 FCRI-SF 为因变量，SWB 和 BRS 为解释变量的层次线性回归分析表明，SWB 影响 FCRI-SF 得分，是 FCR 的潜在预测因子。中介分析表明，SWB 部分中介了心理弹性与 FCR 之间的关系。
尽管 COVID-19 大流行导致乳腺癌幸存者无法维持医疗随访，但具有较高 SWB 和心理弹性得分的患者经历的 FCR 较少。应努力提高被诊断患有乳腺癌患者的心理弹性和 SWB。
