Henan Provincial Key Medicine Laboratory of Nursing, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Department of Publicity, Zhengzhou Vocational University of Information and Technology, Zhengzhou, Henan, China.
Front Public Health. 2023 Aug 28;11:1207097. doi: 10.3389/fpubh.2023.1207097. eCollection 2023.
While previous studies have revealed a positive association between resilience and quality of life in advanced cancer survivors, the mechanisms of the relationship is still unclear. This study aimed to explore the relationships between resilience, social support, spirituality, and quality of life and determine the multiple mediation effects of social support and spirituality on the relationship between resilience and quality of life.
With 286 advanced cancer survivors, a cross-sectional, correlational survey was adopted using convenience sampling. Resilience, social support, spirituality, and quality of life were evaluated by self-report questionnaires. The PROCESS macro for SPSS was used to test the multiple mediation model.
The scores for resilience, social support, spirituality and quality of life were positively correlated with one another. Resilience was found to be directly impact quality of life. Meanwhile, the relationship between resilience and quality of life was mediated by social support (effect = 0.067, 95% CI [0.019, 0.120]) and by spirituality (effect = 0.221, 95% CI [0.134, 0.332]), respectively, and by these two serially (effect = 0.036, 95% CI [0.015, 0.067]).
Social support and spirituality played multiple mediating roles in the relationship between resilience and quality of life. Interventions aimed at increasing resilience, and then boosting social support and spirituality may be beneficial for promoting quality of life of advanced cancer survivors.
尽管先前的研究表明，在晚期癌症幸存者中，韧性与生活质量之间存在正相关关系，但两者之间的关系机制尚不清楚。本研究旨在探讨韧性、社会支持、灵性与生活质量之间的关系，并确定社会支持和灵性对韧性与生活质量之间关系的多重中介作用。
采用便利抽样法，对 286 名晚期癌症幸存者进行横断面相关性调查。采用自我报告问卷评估韧性、社会支持、灵性和生活质量。采用 SPSS 的 PROCESS 宏检验多重中介模型。
韧性、社会支持、灵性和生活质量得分之间呈正相关。韧性与生活质量直接相关。同时，韧性与生活质量的关系分别通过社会支持（效应 = 0.067，95%CI [0.019, 0.120]）和灵性（效应 = 0.221，95%CI [0.134, 0.332]）得到中介，且通过这两者串联得到中介（效应 = 0.036，95%CI [0.015, 0.067]）。
社会支持和灵性在韧性与生活质量之间的关系中发挥了多重中介作用。旨在提高韧性，继而增强社会支持和灵性的干预措施可能有益于提高晚期癌症幸存者的生活质量。
