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一种近红外荧光探针,通过顺序检测半胱氨酸和 H.,准确诊断癌症。

A near-infrared fluorescent probe for accurately diagnosing cancer by sequential detection of cysteine and H.

机构信息

Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, 411105, P. R. China.

出版信息

Chem Commun (Camb). 2021 May 14;57(39):4811-4814. doi: 10.1039/d1cc01228b. Epub 2021 Apr 16.

DOI:10.1039/d1cc01228b
PMID:33982685
Abstract

A near-infrared fluorescent probe, CyAc, is synthesized for accurately diagnosing cancer in vivo by sequential detection of Cys and H. CyAc can not only achieve a good distinction between normal cells and cancer cells, but also distinguish normal mice from tumor mice.

摘要

一种近红外荧光探针 CyAc 被合成,用于通过顺序检测半胱氨酸和 H 来准确诊断体内癌症。CyAc 不仅可以实现正常细胞和癌细胞的良好区分,还可以区分正常小鼠和肿瘤小鼠。

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