Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Centre, Taipei.
Department of Paediatric Surgery, Tri-Service General Hospital, National Defense Medical Centre, Taipei.
J Int Med Res. 2021 May;49(5):3000605211014797. doi: 10.1177/03000605211014797.
The coexistence of imperforate hymen and vaginal septum is rare and their ability to mimic malignant manifestations have not been frequently reported. This current case report describes a 13-year-old girl that presented with cyclic abdominal pain for 6 months. She was found to have a huge mass via abdominal plain film X-ray and sonography, with inexplicably high levels of serum carcinoembryonic antigen, cancer antigen (CA)-19-9 and CA-125. Pelvic computed tomography imaging disclosed two huge cystic lesions in the uterine and upper vaginal cavities. Surgical intervention conformed the diagnosis of a concurrent imperforate hymen and transverse vaginal septum, echoing the imaging findings of haematocolpometra. Her tumour marker levels gradually returned to normal after surgery. This rare case of concomitant imperforate hymen and transverse vaginal septum highlights that haematocolpometra, a benign disease that might mimic malignancy, should be taken into consideration in any adolescent females with an abdominal mass and amenorrhoea to ensure an early diagnosis and timely appropriate management.
处女膜闭锁和阴道横隔并存的情况较为罕见，且它们能够模拟恶性表现的情况也并不常见。本病例报告描述了一名 13 岁女孩，她因周期性腹痛就诊，已持续 6 个月。腹部平片 X 线和超声检查发现了一个巨大的肿块，同时血清癌胚抗原、癌抗原（CA）-19-9 和 CA-125 水平异常升高。盆腔 CT 成像显示子宫和阴道上段有两个巨大的囊性病变。手术干预证实了同时存在处女膜闭锁和横向阴道隔的诊断，与影像学表现的阴道积血相一致。手术后，她的肿瘤标志物水平逐渐恢复正常。这例罕见的处女膜闭锁和横向阴道隔并存病例强调，阴道积血是一种良性疾病，但可能会被误诊为恶性疾病，因此对于任何有腹部肿块和闭经的青春期女性，都应考虑到该病，以确保早期诊断和及时适当的治疗。
