Labro Guylaine, Jandeaux Louise Marie, Rusu Andreea, Virot Edouard, Pointurier Valentin, Pinto Luis, Mathien Cyrille, Debliquis Agathe, Harzallah Ines, Mootien Joy, Drenou Bernard, Kuteifan Khaldoun
Service de Reanimation Medicale, Groupe Hospitalier de la Region Mulhouse Sud Alsace, Mulhouse, France.
Departement d'Hematologie, Groupe Hospitalier de la region Mulhouse Sud Alsace, Mulhouse, France.
J Med Cases. 2020 Jul;11(7):211-214. doi: 10.14740/jmc3520. Epub 2020 Jun 29.
We report six cases of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, admitted to intensive care unit (ICU), for whom bone marrow aspirate revealed hemophagocytosis. We compared their clinical presentation and laboratory findings to those that can be encountered during a hemophagocytic lymphohistiocytosis. These observations might evoke a macrophage activation mechanism different from the one encountered in the hemophagocytic lymphohistiocytosis (HLH).
我们报告了6例感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）并入住重症监护病房（ICU）的患者，其骨髓穿刺显示噬血细胞现象。我们将他们的临床表现和实验室检查结果与噬血细胞性淋巴组织细胞增生症时可能出现的情况进行了比较。这些观察结果可能提示存在一种不同于噬血细胞性淋巴组织细胞增生症（HLH）中所见的巨噬细胞激活机制。
