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面部双侧瘫作为新型冠状病毒感染罕见的迟发性神经表现

Facial Diplegia as a Rare Late Neurologic Manifestation of SARS-CoV-2 Infection.

作者信息

Judge Casey, Moheb Negar, Castro Apolo Ramiro, Dupont Joy L, Gessner Michelle L, Yacoub Hussam A

机构信息

Department of Neurology, Lehigh Valley Health Network, Allentown, PA, USA.

出版信息

J Neurol Res. 2020 Dec;10(6):235-236. doi: 10.14740/jnr606. Epub 2020 Dec 9.

Abstract

Multiple recent publications have reported numerous neurologic complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Among these is Guillain-Barre syndrome and its variants, including facial diplegia. In this case we present a patient with facial diplegia following a confirmed SARS-CoV-2 infection. The patient initially presented with respiratory symptoms and subsequently developed bilateral facial weakness approximately 3 weeks later prompting an emergency department (ED) visit. Extensive laboratory and imaging workup was negative for other etiologies. Cerebrospinal fluid (CSF) analysis was notable only for mild elevation in white blood cells and protein. Patients with acute neurologic symptoms should be evaluated carefully regarding recent infections or possible exposures to help identify and minimize late complications of this novel virus.

摘要

最近有多项出版物报道了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染的众多神经系统并发症。其中包括吉兰-巴雷综合征及其变体,包括双侧面瘫。在本病例中,我们报告了1例确诊SARS-CoV-2感染后出现双侧面瘫的患者。该患者最初出现呼吸道症状,约3周后出现双侧面部无力,随后前往急诊科就诊。广泛的实验室检查和影像学检查未发现其他病因。脑脊液(CSF)分析仅显示白细胞和蛋白质轻度升高。对于出现急性神经系统症状的患者,应仔细评估其近期感染情况或可能的暴露史,以帮助识别并尽量减少这种新型病毒的晚期并发症。

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