Department of Neurology, Fundación Cardioinfantil (FCI), 110131, Bogotá, Colombia.
Departamento de Medicina Física y Rehabilitación,, Departamento de Neurofisiología, FCI, 110131, Bogotá, Colombia.
J Med Case Rep. 2021 Nov 15;15(1):558. doi: 10.1186/s13256-021-03120-w.
The new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) owing to its similarity to the previous severe acute respiratory syndrome (SARS), is characterized by causing, in most patients, nonspecific symptoms similar to those of the common flu. It has been reported that many coronavirus disease 2019 (COVID-19) patients presented neurological symptoms that involve the central and peripheral nervous systems. In addition, there have been several reports of patients who presented Guillain-Barré syndrome related to COVID-19 , with sensory and motor compromise in the extremities.
In this report, we describe a rare case of Guillain-Barré syndrome in a 50-year-old Hispanic male with bilateral facial palsy as the only neurological manifestation, following SARS-CoV-2 infection. A complete neurophysiological study showed severe axonal neuropathy of the right and left facial nerves.
Regardless of severity, clinicians must to be aware of any neurological manifestation generated by COVID-19 and start performing more neurophysiological tests to determine if the infection induces an axonal, myelin, or mixed involvement of the peripheral nervous system.
新型冠状病毒(SARS-CoV-2)因其与之前的严重急性呼吸综合征(SARS)相似而被称为严重急性呼吸综合征冠状病毒 2,其特征在于大多数患者出现非特异性症状,类似于普通流感。据报道,许多 COVID-19 患者出现涉及中枢和外周神经系统的神经系统症状。此外,已有几例报告 COVID-19 患者出现与格林-巴利综合征相关的疾病,四肢有感觉和运动功能障碍。
在本报告中,我们描述了一例罕见的 COVID-19 后发生的格林-巴利综合征病例,一名 50 岁的西班牙裔男性,仅表现为双侧面瘫。一项完整的神经生理学研究显示右侧和左侧面神经严重轴索性神经病。
无论严重程度如何,临床医生都必须意识到 COVID-19 引起的任何神经系统表现,并开始进行更多的神经生理学测试,以确定感染是否引起周围神经系统的轴索、髓鞘或混合性受累。