足月龄时的身体成分与早产儿 2 岁时贝利评分的相关性。

Association between body composition at term equivalent age and Bayley scores at 2 years in preterm infants.

机构信息

Neonatal Intensive Care Unit, Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.

Division of Child Neurology and Psychiatry, Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.

出版信息

J Perinatol. 2021 Aug;41(8):1852-1858. doi: 10.1038/s41372-021-01074-x. Epub 2021 May 13.

DOI:10.1038/s41372-021-01074-x

PMID:33986476

Abstract

OBJECTIVE

To evaluate whether in a historical cohort of preterm infants, body composition at term equivalent age (TEA) correlated with Bayley scores at 2 years of corrected age.

STUDY DESIGN

Ninety-five preterm babies were admitted to our neonatal intensive unit and underwent air-displacement plethysmography assessment at TEA. Of these, 74 completed Bayley tests at 2 years. We used multiple linear regression analysis to assess the association of body composition with Bayley scores.

RESULTS

Mean gestational age and birthweight of our population were respectively 29.8 (±2.2) weeks and 1150 (±330) grams. Higher fat-free mass (FFM) z-score was associated with higher language (adjusted r = 0.28, p = 0.03) and motor composite scores (adjusted r = 0.33, p = 0.03) in both univariate and multiple regression analysis including birth weight, sex, maternal university degree, mechanical ventilation, and bilingualism.

CONCLUSIONS

In our study FFM at term equivalent age was associated with higher Bayley composite motor and language scores at 2 years.

摘要

目的

评估在早产儿的历史队列中，胎龄相当（TEA）时的身体成分是否与校正 2 岁时的贝利（Bayley）评分相关。

研究设计

95 名早产儿被收入我们的新生儿重症监护病房，并在 TEA 时进行空气置换体积描记法评估。其中，74 名在 2 岁时完成了贝利测试。我们使用多元线性回归分析来评估身体成分与贝利评分之间的关系。

结果

我们人群的平均胎龄和出生体重分别为 29.8（±2.2）周和 1150（±330）克。较高的去脂体重（FFM）z 评分与较高的语言（调整后的 r=0.28，p=0.03）和运动综合评分（调整后的 r=0.33，p=0.03）相关，在包括出生体重、性别、母亲的大学学历、机械通气和双语的单变量和多变量回归分析中均如此。