Yuan Mei, Guo Yi-Sha, Han Yu, Gao Zhen-Kun, Shen Xin-Ya, Bi Xia
Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, 201318, China.
Shanghai University of Sport, Shanghai, 200438, China.
Behav Brain Res. 2021 Jul 23;410:113357. doi: 10.1016/j.bbr.2021.113357. Epub 2021 May 11.
Post-stroke cognitive impairment (PSCI) is one of the most common complications of stroke, it is also an important reason for the poor prognosis in stroke patients with motor and speech dysfunction. Enriched Environment (EE), a novel and easy-to-implement rehabilitation treatment strategy, is thought to be a potential intervention for PSCI recently. In this paper, we review the therapeutic effects and related mechanisms of EE in PSCI from the level of animal research and clinical application. Besides, we further discuss the application prospects and limitations of EE in PSCI patients.
中风后认知障碍（PSCI）是中风最常见的并发症之一，也是导致运动和言语功能障碍的中风患者预后不良的重要原因。丰富环境（EE）作为一种新颖且易于实施的康复治疗策略，最近被认为是PSCI的一种潜在干预措施。在本文中，我们从动物研究和临床应用层面综述了EE对PSCI的治疗效果及相关机制。此外，我们还进一步探讨了EE在PSCI患者中的应用前景和局限性。
