Research Center of Clinical and Translational Medicine, Fifth Medical Center of Chinese, PLA General Hospital, 100 Middle Street of 4th West Ring Road, Beijing, 100039, China.
Treatment and Research Center for Infectious Diseases, Fifth Medical Center of Chinese, PLA General Hospital, 100 Middle Street of 4th West Ring Road, Beijing, 100039, China.
Eur J Med Res. 2021 May 14;26(1):45. doi: 10.1186/s40001-021-00515-9.
Hematological comparison of coronavirus disease (COVID-19) and other viral pneumonias can provide insights into COVID-19 treatment.
In this retrospective case-control single-center study, we compared the data of 126 patients with viral pneumonia during different outbreaks [severe acute respiratory syndrome (SARS) in 2003, influenza A (H1N1) in 2009, human adenovirus type 7 in 2018, and COVID-19 in 2020].
One of the COVID-19 characteristics was a continuous decline in the hemoglobin level. The neutrophil count was related to the aggravation of COVID-19 and SARS. Thrombocytopenia occurred in patients with SARS and severe COVID-19 even at the recovery stage. Lymphocytes were related to the entire course of adenovirus infection, recovery of COVID-19, and disease development of SARS.
Dynamic changes in hematological counts could provide a reference for the pathogenesis and prognosis of pneumonia caused by respiratory viruses in clinics.
比较冠状病毒病（COVID-19）和其他病毒性肺炎的血液学特征可以深入了解 COVID-19 的治疗方法。
本回顾性病例对照单中心研究比较了在不同疫情期间（2003 年 SARS、2009 年甲型 H1N1 流感、2018 年人腺病毒 7 型和 2020 年 COVID-19）126 例病毒性肺炎患者的数据。
COVID-19 的特征之一是血红蛋白水平持续下降。中性粒细胞计数与 COVID-19 和 SARS 的加重有关。SARS 和重症 COVID-19 患者在恢复期也会出现血小板减少。淋巴细胞与腺病毒感染的整个过程、COVID-19 的恢复和 SARS 的疾病进展有关。
血液学计数的动态变化可为临床呼吸系统病毒引起的肺炎的发病机制和预后提供参考。
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