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巴西南部葡萄园农民职业性接触农药后的元素血浆含量和尿排泄。

Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil.

机构信息

Postgraduate Program in Biosciences and Physiopathology, State University of Maringá, Maringá, Paraná, Brazil.

Postgraduate Program in Health Sciences, State University of Maringá, Maringá, Paraná, Brazil.

出版信息

Environ Sci Pollut Res Int. 2021 Oct;28(37):51841-51853. doi: 10.1007/s11356-021-14384-6. Epub 2021 May 15.

Abstract

This is a cross-sectional study with data and biological material collection from vineyard farmers in southern Brazil. An interview was carried out through a questionnaire developed according to the reference guide of the state government. Plasma and urine samples were screened for Aluminum, Chromium, Manganese, Copper, Nickel, Cobalt, Zinc, Arsenic, Selenium, Cadmium, Antimony, Barium, Mercury, Lead and Uranium, with a technique for fast determination of these elemental contents in biological material utilizing dynamic reaction cell inductively coupled mass spectrometry. Principal component analysis was used to identify associations between these elemental contents in biological samples and the information obtained from the interviews. The farmers showed some trace elements in plasma and urine at a higher concentration than unexposed populations from other studies. This study highlights recent findings of trace elements in biological material and their association with characteristics of pesticide use. In addition, it also contributes to the gap in the literature regarding trace elements content in plasma and urine of workers exposed to pesticides.

摘要

本研究为横断面研究,数据和生物材料采集自巴西南部的葡萄园农民。通过问卷调查进行访谈,该问卷是根据州政府的参考指南制定的。对血浆和尿液样本进行了铝、铬、锰、铜、镍、钴、锌、砷、硒、镉、锑、钡、汞、铅和铀的筛选,采用动态反应池电感耦合质谱法快速测定生物材料中这些元素的含量。主成分分析用于识别生物样本中这些元素含量与访谈中获得的信息之间的关联。与其他研究中的未暴露人群相比,农民的血浆和尿液中的一些微量元素浓度更高。本研究强调了生物材料中微量元素的最新发现及其与农药使用特征的关联。此外,它还弥补了关于接触农药的工人血浆和尿液中微量元素含量的文献空白。

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