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印度全国范围内的血液需求人群估计。

A national level estimation of population need for blood in India.

机构信息

Christian Medical College, Vellore, India.

Christian Medical Association of India (CMAI), New Delhi, India.

出版信息

Transfusion. 2021 Jun;61(6):1809-1821. doi: 10.1111/trf.16369. Epub 2021 May 15.

DOI:10.1111/trf.16369
PMID:33991428
Abstract

BACKGROUND

The population need for blood is the total volume required to transfuse all the individuals who need transfusion in a defined population over a defined period. The clinical demand will arise when people with a disease or condition who require transfusion, access healthcare services, and subsequently the clinicians request blood. Essentially, the conversion of need to demand must be maximum to avoid preventable mortality and morbidity. The study estimated the population need for blood in India.

METHODS

The methodology included a comprehensive literature review to determine the diseases and conditions requiring transfusion, the population at risk, and prevalence or incidence; and Delphi method to estimate the percentage of people requiring transfusion, and the quantum.

RESULTS

The estimated annual population need was 26.2 million units (95% CI; 17.9-38.0) of whole blood to address the need for red cells and other components after the separation process. The need for medical conditions was 11.0 million units (95% CI:8.7-14.7), followed by surgery 6.6 million (95% CI:3.8-10.0), pediatrics 5.0 million (95% CI:3.5-7.0), and obstetrics and gynecology 3.6 million units (95% CI:1.9-6.2). The gap between need and demand which depends upon the access and efficiency of healthcare service provision was estimated at 13 million units.

CONCLUSION

The study brings evidence to highlight the gap between need and demand and the importance of addressing it. It cannot be just the responsibility of blood transfusion or health systems, it requires a multi-sectoral approach to address the barriers affecting the conversion of need to clinical demand for blood.

摘要

背景

人口的血液需求是指在特定时期内,特定人群中所有需要输血的个体所需的总血量。当患有疾病或需要输血的人需要获得医疗服务并随后请求输血时,就会产生临床需求。本质上,必须将需求转化为最大需求,以避免可预防的死亡和发病。本研究旨在估算印度的人口血液需求。

方法

该方法包括对需要输血的疾病和病症、高危人群以及患病率或发病率进行全面文献回顾;并采用德尔菲法估计需要输血的人群比例和数量。

结果

估计每年需要 2620 万单位(95%CI:1790-3800)全血来满足分离后红细胞和其他成分的需求。医疗条件的需求为 1100 万单位(95%CI:870-1470),其次是手术需求 660 万单位(95%CI:380-1000),儿科需求 500 万单位(95%CI:350-700),妇产科需求 360 万单位(95%CI:190-620)。需求与供给之间的差距取决于医疗服务的获取和效率,估计为 1300 万单位。

结论

本研究提供了证据,突出了需求与供给之间的差距以及解决这一差距的重要性。这不仅仅是输血或卫生系统的责任,需要采取多部门方法来解决影响将需求转化为临床血液需求的障碍。

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