Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway.
Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway.
Sleep Med. 2021 Jul;83:89-98. doi: 10.1016/j.sleep.2021.04.028. Epub 2021 Apr 28.
Sleep and physical activity changes are common in pregnancy, but longitudinal data starting before conception are scarce. Our aim was to determine the changes of the daily total sleep time (TST) and physical activity duration (PAD) from before conception to end of pregnancies in respect of pregestational maternal factors.
This longitudinal observational study formed part of the CONIMPREG research project and recruited healthy women planning to become pregnant. Sleep and physical activity were recorded around-the-clock for ≥4 days via actigraphy before conception and during each trimester of pregnancy. Data were adjusted according to pregestational maternal body composition, parity and age.
Among 123 women with eligible data, the unadjusted mean (95% confidence interval) TST increased from 415.3 min (405.5-425.2 min) before conception to 458.0 min (445.4-470.6 min) in the 1 trimester, remaining high through the 2 and 3 trimesters. Variation was substantial before conception (±2SD range: 307-523 min). The unadjusted mean PAD before conception was 363.7 min (±2SD range: 120-608 min), decreasing sharply to 262.1 min in the first trimester and more gradually thereafter. Vigorous and moderate activity decreased more than light activity. TST and PAD were significantly associated with age, parity, and pregestational body fat percentage; lean body mass was negatively correlated with TST. Results were generally unaffected by seasonal variations.
Marked variations were found in pregestational TST and PAD. Healthy women slept ≥30 min longer during pregnancy, while PAD decreased by ≥ 90 min in early pregnancy and continued to decrease thereafter.
睡眠和身体活动的变化在妊娠期间很常见，但在受孕前开始的纵向数据却很少。我们的目的是确定从受孕前到妊娠结束时，每日总睡眠时间（TST）和身体活动时间（PAD）的变化，以了解孕前母体因素的影响。
这项纵向观察性研究是 CONIMPREG 研究项目的一部分，招募了计划怀孕的健康女性。在受孕前和妊娠每个 trimester 期间，通过活动记录仪全天候记录至少 4 天的睡眠和身体活动情况。数据根据孕前母体身体成分、产次和年龄进行了调整。
在 123 名符合条件的数据女性中，未经调整的平均（95%置信区间）TST 从受孕前的 415.3 分钟（405.5-425.2 分钟）增加到 1 trimester 的 458.0 分钟（445.4-470.6 分钟），并在 2 和 3 trimester 期间保持高位。受孕前的变化很大（±2SD 范围：307-523 分钟）。受孕前的未经调整的平均 PAD 为 363.7 分钟（±2SD 范围：120-608 分钟），在第一个 trimester 急剧下降至 262.1 分钟，此后逐渐下降。剧烈活动和中度活动的减少量超过轻度活动。TST 和 PAD 与年龄、产次和孕前体脂百分比显著相关；瘦体重与 TST 呈负相关。结果不受季节性变化的影响。
在孕前 TST 和 PAD 中发现了明显的变化。健康女性在怀孕期间的睡眠时间增加了≥30 分钟，而 PAD 在早期妊娠时减少了≥90 分钟，此后继续减少。
