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肝硬变合并洋葱伯克霍尔德菌复合群引起的自发性细菌性腹膜炎。

Liver Cirrhosis Complicated by Spontaneous Bacterial Peritonitis Caused by the Burkholderia cepacia Complex.

机构信息

Department of Gastroenterology, Tokyo-Kita Medical Center, Japan.

出版信息

Intern Med. 2021 Nov 1;60(21):3435-3440. doi: 10.2169/internalmedicine.7170-21. Epub 2021 May 14.

Abstract

A 79-year-old man with underlying alcoholic liver cirrhosis presented with complaints of a fever, abdominal pain, and difficulty walking. A diagnostic work-up revealed liver atrophy and chylous ascites, and spontaneous bacterial peritonitis (SBP) was diagnosed based on the cell and neutrophil counts. The Burkholderia cepacia complex (Bcc) was detected on blood and ascitic fluid cultures. Although broad-spectrum antibiotic therapy was initiated, the infection was difficult to control, and the patient died of multiple organ failure. Bcc is often multidrug-resistant and difficult to treat. SBP caused by Bcc has been rarely reported and may have a serious course, thus necessitating caution.

摘要

一位 79 岁的男性,患有酒精性肝硬化基础疾病,主诉发热、腹痛和行走困难。诊断性检查发现肝脏萎缩和乳糜性腹水,并根据细胞和中性粒细胞计数诊断为自发性细菌性腹膜炎(SBP)。血液和腹水培养检测到洋葱伯克霍尔德菌复合群(Bcc)。尽管开始了广谱抗生素治疗,但感染难以控制,患者死于多器官衰竭。Bcc 通常具有多重耐药性,难以治疗。由 Bcc 引起的 SBP 很少见报道,可能具有严重的病程,因此需要谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6114/8627796/d68dc78b33ae/1349-7235-60-3435-g001.jpg

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