Batouli Seyed Amir Hossein, Sisakhti Minoo, Haghshenas Shirin, Dehghani Hamed, Sachdev Perminder, Ekhtiari Hamed, Kochan Nicole, Wen Wei, Leemans Alexander, Kohanpour Mohsen, Oghabian Mohammad Ali
Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Departmen of Neuroimaging and Analysis, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Basic Clin Neurosci. 2021 Jan-Feb;12(1):115-132. doi: 10.32598/bcn.12.1.1774.2. Epub 2021 Jan 1.
The Iranian Brain Imaging Database (IBID) was initiated in 2017, with 5 major goals: provide researchers easy access to a neuroimaging database, provide normative quantitative measures of the brain for clinical research purposes, study the aging profile of the brain, examine the association of brain structure and function, and join the ENIGMA consortium. Many prestigious databases with similar goals are available. However, they were not done on an Iranian population, and the battery of their tests (e.g. cognitive tests) is selected based on their specific questions and needs.
The IBID will include 300 participants (50% female) in the age range of 20 to 70 years old, with an equal number of participants (#60) in each age decade. It comprises a battery of cognitive, lifestyle, medical, and mental health tests, in addition to several Magnetic Resonance Imaging (MRI) protocols. Each participant completes the assessments on two referral days.
The study currently has a cross-sectional design, but longitudinal assessments are considered for the future phases of the study. Here, details of the methodology and the initial results of assessing the first 152 participants of the study are provided.
IBID is established to enable research into human brain function, to aid clinicians in disease diagnosis research, and also to unite the Iranian researchers with interests in the brain.
伊朗脑成像数据库(IBID)于2017年启动,有5个主要目标:为研究人员提供便捷的神经成像数据库访问途径;为临床研究目的提供大脑的标准化定量测量数据;研究大脑的老化特征;研究大脑结构与功能的关联;加入增强神经影像基因组学联盟(ENIGMA)。有许多具有类似目标的著名数据库。然而,这些数据库并非针对伊朗人群建立,且其测试组合(如认知测试)是根据其特定问题和需求选定的。
IBID将纳入300名年龄在20至70岁之间的参与者(50%为女性),每个十年年龄段的参与者数量相等(各60名)。除了几个磁共振成像(MRI)方案外,它还包括一系列认知、生活方式、医学和心理健康测试。每位参与者在两个指定日期完成评估。
该研究目前采用横断面设计,但在研究的未来阶段考虑进行纵向评估。在此,提供了该研究的方法细节以及对前152名参与者进行评估的初步结果。
IBID的建立旨在促进对人类脑功能的研究,帮助临床医生进行疾病诊断研究,并将对大脑研究感兴趣的伊朗研究人员团结起来。