Khoshbakht Sareh, Motejaded Fatemeh, Karimi Sareh, Jalilvand Narjes, Ebrahimzadeh-Bideskan Alireza
Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Basic Med Sci. 2021 Mar;24(3):322-330. doi: 10.22038/ijbms.2021.45358.10554.
Electromagnetic field (EMF) emitted by mobiles may affect the male reproductive system. Selenium, as an antioxidant, may protect against electromagnetic field-induced tissue damage. Theis study aimed to investigate the effects of selenium on rat testis exposed to electromagnetic fields.
Twenty-four male Wistar rats were divided into four groups, namely EM group (2100 MHZ), EM/SE group (2100 MHZ + selenium (0.2 mg/kg), SE group (selenium 0.2 mg/kg), CONT (control group). Serum LH, FSH, testosterone, leptin and aromatase levels, testis weight and volume index, sperm parameters (count and abnormal percent), seminiferous tubule diam¬eters, germinal epithelia thickness, immunoreactivity of leptin receptor and caspase-3 (for apoptotic cells in germinal epithelium) were investigated.
Our results showed that serum LH, FSH, GnRH, testosterone level, sperm count, germinal epithelium thickness, and seminiferous tubule diameter were significantly declined in the EM group compared with the CONT group (<0.05). However, in the EM group, the serum leptin level, sperm abnormality, aromatase enzyme level, apoptotic cells, and leptin receptor were increased compared with the CONT group (<0.05). Furthermore, an increase in sperm count, germinal epithelium thickness, seminiferous diameters, serum LH, FSH, and GnRH, and testosterone levels, and a significant decrease in sperm abnormality, leptin receptor and apoptotic cells in the EM/SE group compared with the EM group were also observed (<0.05).
This study showed that electromagnetic radiation may have detrimental impacts on the male reproductive system, which can be prevented by use of selenium.
手机发出的电磁场（EMF）可能会影响男性生殖系统。硒作为一种抗氧化剂，可能会预防电磁场引起的组织损伤。本研究旨在探讨硒对暴露于电磁场的大鼠睾丸的影响。
将24只雄性Wistar大鼠分为四组，即EM组（2100兆赫）、EM/SE组（2100兆赫+硒（0.2毫克/千克））、SE组（硒0.2毫克/千克）、CONT组（对照组）。检测血清促黄体生成素（LH）、促卵泡生成素（FSH）、睾酮、瘦素和芳香化酶水平、睾丸重量和体积指数、精子参数（计数和异常百分比）、生精小管直径、生精上皮厚度、瘦素受体和半胱天冬酶-3的免疫反应性（用于生精上皮中的凋亡细胞）。
我们的结果显示，与CONT组相比，EM组的血清LH、FSH、促性腺激素释放激素（GnRH）、睾酮水平、精子计数、生精上皮厚度和生精小管直径显著下降（<0.05）。然而，与CONT组相比，EM组的血清瘦素水平、精子异常、芳香化酶水平、凋亡细胞和瘦素受体增加（<0.05）。此外，与EM组相比，EM/SE组的精子计数、生精上皮厚度、生精直径、血清LH、FSH和GnRH以及睾酮水平增加，精子异常、瘦素受体和凋亡细胞显著减少（<0.05）。
本研究表明，电磁辐射可能对男性生殖系统产生有害影响，而使用硒可以预防这种影响。
