[紫外线照射后胸腺淋巴细胞死亡过程的生化表现特征]
[Characteristics of the biochemical manifestation of the process of thymic lymphocyte death following UV irradiation].
作者信息
Soldatenkov V A, Trebenok Z A, Filippovich I V
出版信息
Radiobiologiia. 1988 May-Jun;28(3):310-4.
PMID:3399629
Abstract
Thymus lymphocyte death caused by UV-radiation is a function of radiation dose. Thymocyte death induced by UV-light, in contrast to gamma-radiation, is not accompanied by chromatin degradation. With UV-irradiation, irreparable DNA breaks are not responsible for thymocyte death. Cycloheximide, but not cysteamine, prevents the UV-induced cell death.
摘要
紫外线辐射导致的胸腺淋巴细胞死亡是辐射剂量的函数。与γ辐射不同，紫外线诱导的胸腺细胞死亡不伴有染色质降解。紫外线照射时，不可修复的DNA断裂并非胸腺细胞死亡的原因。环己酰亚胺而非半胱胺可阻止紫外线诱导的细胞死亡。
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