Linehan I P, Russell R C, Hobsley M
Department of Surgical Studies, Middlesex Hospital, London, England, United Kingdom.
Surg Gynecol Obstet. 1988 Aug;167(2):114-8.
Some patients have postoperative nutritional problems after a pancreatoduodenectomy. These problems have been attributed without objective evidence to the partial gastrectomy that is performed at the time of the pancreatoduodenectomy. The dumping syndrome has been implicated, and the results of this study determine, for the first time, the role of the dumping syndrome in pancreatic surgical procedures. Sixty-four dumping provocation tests have been performed upon patients with pancreatic disease or after pancreatic surgical treatment. Three patients had the dumping syndrome, and in eight, the result of the test was equivocal. Results of the present study demonstrate an incidence of dumping syndrome after pancreatoduodenectomy of 10 per cent; however, in none of these patients, was the dumping syndrome a significant problem. There was no instance of the dumping syndrome after pylorus-preserving or duodenum-preserving pancreatectomy. It is concluded that, contrary to previous assumptions, the dumping syndrome does not contribute to long term postoperative problems after pancreatic surgical procedures.
一些患者在胰十二指肠切除术后会出现术后营养问题。这些问题在没有客观证据的情况下被归因于胰十二指肠切除术时所进行的部分胃切除术。倾倒综合征被认为与之有关,而本研究的结果首次确定了倾倒综合征在胰腺外科手术中的作用。已对患有胰腺疾病或接受胰腺外科治疗后的患者进行了64次倾倒激发试验。3名患者出现倾倒综合征,8名患者的试验结果不明确。本研究结果表明,胰十二指肠切除术后倾倒综合征的发生率为10%;然而,在这些患者中,倾倒综合征均不是一个严重问题。保留幽门或保留十二指肠的胰腺切除术后未出现倾倒综合征的情况。得出的结论是,与先前的假设相反,倾倒综合征不会导致胰腺外科手术后的长期术后问题。