University of California, Los Angeles, USA.
Stony Brook University, USA.
J Health Psychol. 2022 Aug;27(9):2013-2026. doi: 10.1177/13591053211014583. Epub 2021 May 18.
Individuals with Mast Cell Activation Syndrome (MCAS), a rare chronic disease, experience unpredictable physical symptoms and diagnostic challenges resulting in poor emotional states. The prevalence and correlates of depressive symptoms were examined among 125 participants who completed the CES-D and relevant instruments. The majority reported a clinically-significant level of depression which was especially common among younger participants and those who reported greater loneliness or more disease-specific stressors. Greater magnitude of depressive symptoms was associated with greater illness intrusiveness, less social support, and lower optimism. Results highlight the value of interventions targeting loneliness and stressors unique to this population.
患有肥大细胞活化综合征 (MCAS) 的个体患有罕见的慢性疾病，会经历不可预测的身体症状和诊断挑战，导致情绪不佳。本研究调查了 125 名完成 CES-D 和相关工具的参与者中抑郁症状的患病率和相关性。大多数参与者报告存在具有临床意义的抑郁水平，尤其是在年轻参与者和那些报告孤独感更强或更多疾病特异性压力源的参与者中更为常见。抑郁症状的严重程度与疾病侵扰度更高、社会支持度更低和乐观程度更低相关。研究结果突显了针对该人群特有的孤独感和压力源的干预措施的价值。
