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Characteristics of an attenuated Anaplasma marginale of deer origin as an anaplasmosis vaccine.

作者信息

Kuttler K L, Zaugg J L

机构信息

USDA, ARS, University of Idaho, Caldwell 83605.

出版信息

Trop Anim Health Prod. 1988 May;20(2):85-91. doi: 10.1007/BF02242231.

DOI:10.1007/BF02242231
PMID:3400115
Abstract

A fully virulent field Anaplasma marginale isolate, passaged to a splenectomised white tailed deer, lost virulence for cattle after 18 months in the non-bovine host. This attenuated A. marginale produced a mild response in four 18-month-old Holstein steers characterised by an average 2.4% parasitaemia, a 13% drop in PCV and a positive serological response. All vaccinated steers were immune to challenge with a fully virulent, heterologous A. marginale when compared with non-vaccinated controls.

摘要

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本文引用的文献

1
Comparison of three methods of immunization against bovine anaplasmosis: evaluation of protection afforded against field challenge exposure.三种牛无浆体病免疫方法的比较：评估针对田间攻击暴露所提供的保护作用。
Am J Vet Res. 1980 Jul;41(7):1066-8.
2
Anaplasma infections in wild and domestic ruminants: a review.野生和家养反刍动物的无形体感染：综述
J Wildl Dis. 1984 Jan;20(1):12-20. doi: 10.7589/0090-3558-20.1.12.
3
Serologic and clinical responses of premunized, vaccinated, and previously infected cattle to challenge exposure by two different Anaplasma marginale isolates.
冈比亚恩达马牛和戈布拉瘤牛在自然感染蜱虫情况下对不同蜱属的易感性。
Trop Anim Health Prod. 1995 May;27(2):95-105. doi: 10.1007/BF02236320.
经预免疫、接种疫苗和先前感染的牛对两种不同边缘无浆体分离株攻击暴露的血清学和临床反应。
Am J Vet Res. 1984 Nov;45(11):2223-6.
4
A study of the immunological relationship of Anaplasma marginale and Anaplasma centrale.
Res Vet Sci. 1967 Oct;8(4):467-71.
5
Serological relationship of Anaplasma marginale and Anaplasma centrale as measured by the complement-fixation and capillary tube agglutination tests.
Res Vet Sci. 1967 Apr;8(2):207-11.
6
Clinical and hematologic comparison of Anaplasma marginale and Anaplasma centrale infections in cattle.牛边缘无形体和中央无形体感染的临床与血液学比较
Am J Vet Res. 1966 Jul;27(119):941-6.
7
Neonatal immunohemolytic anemia and icterus of calves.
J Am Vet Med Assoc. 1970 Jun 15;156(12):1861-9.
8
Serial passage of an attenuated Anaplasma marginale in splenectomized calves.在脾切除的犊牛中对减毒边缘无形体进行连续传代。
Proc Annu Meet U S Anim Health Assoc. 1969;73:135.
9
Comparative response to premunization using attenuated Anaplasma marginale virulent A. marginale and A. centrale in different age groups.不同年龄组使用减毒边缘无形体、强毒边缘无形体和中央无形体进行免疫前处理后的比较反应。
Trop Anim Health Prod. 1972;4(4):197-203. doi: 10.1007/BF02360111.
10
Cryogenic preservation of Anaplasma marginale with Dimethyl sulfoxide.用二甲基亚砜对边缘无形体进行低温保存。
Am J Vet Res. 1972 Dec;33(12):2557-60.