Yale School of Nursing, 400 West Campus Drive, Orange, CT, 06477, USA.
Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, 3333 California St, San Francisco, CA, 94118, USA.
Mil Med Res. 2021 May 19;8(1):32. doi: 10.1186/s40779-021-00323-6.
Pre-exposure prophylaxis (PrEP) prevents human immunodeficiency virus (HIV) infection, but its use remains low among U.S. military men who have sex with men (MSM), likely due to mis-matching with personal preferences. We conducted a study to characterize preferences to PrEP measures within this population.
HIV-negative military MSM were recruited through a closed, Lesbian, Gay, Bisexual, and Transgendered (LGBT) military social media group. The survey was anonymous, and consisted of five experimentally varied attributes in service delivery: dosing method, provider type, visit location, lab work evaluation location, and dispensing venue. Relative importance and part-worth utility scores were generated using hierarchical bayes (HB) estimation, and the randomized first choice model was used to examine participation interest across eight possible PrEP program scenarios.
A total of 429 participants completed the survey. Among the eight scenarios with varying attributes, the most preferred scenario featured a daily tablet, PrEP injection or implant, along with a military provider, smartphone/telehealth visit, and on-base locations for lab evaluation and medication pick-up. The results also emphasized the importance for providers to be familiar with PrEP prescription knowledge, and to provide interactions sensitive to sexual identity and mental health.
A PrEP program consisting of daily tablet is preferred in military healthcare settings is preferred. Long-acting implants and injections are also desired.
暴露前预防（PrEP）可预防人类免疫缺陷病毒（HIV）感染，但在美国与男性发生性关系的男男性行为者（MSM）中，其使用率仍然较低，这可能是由于与个人偏好不匹配。我们进行了一项研究，以描述该人群对 PrEP 措施的偏好。
通过一个封闭的女同性恋、男同性恋、双性恋和跨性别（LGBT）军事社交媒体群组招募 HIV 阴性的军人 MSM。该调查是匿名的，由服务提供的五个实验性变化属性组成：给药方法、提供者类型、就诊地点、实验室工作评估地点和配药地点。使用分层贝叶斯（HB）估计生成相对重要性和部分价值效用评分，并使用随机首选模型检查八种可能的 PrEP 方案场景中的参与兴趣。
共有 429 名参与者完成了调查。在具有不同属性的八个方案中，最受欢迎的方案是每日服用片剂、PrEP 注射或植入物，以及由军队提供者、智能手机/远程医疗就诊、基地内实验室评估和药物领取地点。结果还强调了提供者熟悉 PrEP 处方知识的重要性，并提供对性身份和心理健康敏感的互动。
在军事医疗保健环境中，首选包含每日片剂的 PrEP 方案。长效植入物和注射剂也很受欢迎。
