Hospital Cárdio Pulmonar, Salvador, BA - Brasil.
Escola Bahiana de Medicina e Saúde Pública, Salvador, BA - Brasil.
Arq Bras Cardiol. 2021 May;116(5):889-895. doi: 10.36660/abc.20190624.
Six-minute step test (6MST) is a simple way to evaluate functional capacity, although it has not been well studied in patients with coronary artery disease (CAD) or heart failure (HF).
Analyze the association between the 6MST and peak oxygen uptake (VO2peak) and develop an equation for estimating VO2peak based on the 6MST, as well as to determine a cutoff point for the 6MST that predicts a VO2peak ≥20 mL.Kg-1.min-1.
In 171 patients who underwent the 6MST and a cardiopulmonary exercise test, correlation, regression, and ROC analysis were used and a p < 0.05 was admitted as significant.
mean age was 60±14 years and 74% were male. Mean left ventricle ejection fraction was 57±16%, 74% had CAD and 28% had HF. Mean VO2peak was 19±6 mL.Kg-1.min-1 and mean 6MST performance was 87±45 steps. Association between 6MST and VO2peak was r 0.69 (p <0.001). The model VO2peak =19.6 + (0.075 x 6MST) - (0.10 x age) for men and VO2peak =19.6 + (0.075 x 6MST) - (0.10 x age) - 2 for women could predict VO2peak based on 6MST results (adjusted R 0.72; adjusted R2 0.53). The most accurate cutoff point for 6MST to predict a VO2peak ≥20 mL.Kg-1.min-1 was >105 steps (AUC 0.85; 95% CI 0.79 -0.90; p <0.001).
An equation for predicting VO2peak based on 6MST results was derived, and a significant association was found between 6MST and VO2peak. The cutoff point for 6MST, which predicts a VO2peak ≥20 mL.Kg-1.min-1, was >105 steps. (Arq Bras Cardiol. 2021; 116(5):889-895).
六分钟步行测试（6MST）是评估功能能力的一种简单方法，尽管它在冠状动脉疾病（CAD）或心力衰竭（HF）患者中尚未得到很好的研究。
分析 6MST 与峰值摄氧量（VO2peak）之间的关系，并建立一个基于 6MST 估计 VO2peak 的方程，以及确定一个预测 VO2peak≥20mL·kg-1·min-1的 6MST 截断值。
在 171 例接受 6MST 和心肺运动试验的患者中，进行了相关性、回归和 ROC 分析，p<0.05 被认为具有统计学意义。
平均年龄为 60±14 岁，74%为男性。平均左心室射血分数为 57±16%，74%有 CAD，28%有 HF。平均 VO2peak 为 19±6 mL·kg-1·min-1，6MST 平均表现为 87±45 步。6MST 与 VO2peak 之间的相关性为 r 0.69（p<0.001）。对于男性，VO2peak=19.6+(0.075×6MST)-(0.10×年龄)；对于女性，VO2peak=19.6+(0.075×6MST)-(0.10×年龄)-2，可以根据 6MST 结果预测 VO2peak（调整 R 0.72；调整 R2 0.53）。预测 VO2peak≥20mL·kg-1·min-1的 6MST 最准确的截断值为>105 步（AUC 0.85；95%CI 0.79-0.90；p<0.001）。
得出了一个基于 6MST 结果预测 VO2peak 的方程，并发现 6MST 与 VO2peak 之间存在显著相关性。预测 VO2peak≥20mL·kg-1·min-1的 6MST 截断值为>105 步。（Arq Bras Cardiol. 2021; 116(5):889-895）。
