Mansour A M, Jampol L M, Logani S, Read J, Henderly D
Department of Ophthalmology, University of Texas Medical Branch, Galveston.
Arch Ophthalmol. 1988 Aug;106(8):1074-7. doi: 10.1001/archopht.1988.01060140230030.
The cotton-wool spot is a common fundus finding in patients with many ocular and systemic diseases. We investigated the characteristics of cotton-wool spots in patients with four major diseases, ie, acquired immunodeficiency syndrome, diabetes mellitus, systemic hypertension, and central retinal vein occlusion, to see if any differences were detected in their number, size, or location. A composite of all the cotton-wool spots for each of these four categories was obtained by computed reconstruction to analyze variations in their distribution and size. The cotton-wool spots had a predilection for the temporal quadrants in the four categories and were smaller in patients with acquired immunodeficiency syndrome than the other groups. Patients with ischemic central retinal vein occlusion had more cotton-wool spots than the other groups. No other definite differences were detected. Cotton-wool spots than the other groups. No other definite differences were detected. Cotton-wool spots seem to be a common pathway following various insults to the retina, most probably of a vaso-occlusive origin.
棉絮斑是许多眼部和全身性疾病患者常见的眼底表现。我们研究了四种主要疾病（即获得性免疫缺陷综合征、糖尿病、系统性高血压和视网膜中央静脉阻塞）患者棉絮斑的特征，以观察其数量、大小或位置是否存在差异。通过计算机重建获得这四类患者所有棉絮斑的合成图像，以分析其分布和大小的变化。棉絮斑在这四类患者中都倾向于出现在颞侧象限，且获得性免疫缺陷综合征患者的棉絮斑比其他组的小。缺血性视网膜中央静脉阻塞患者的棉絮斑比其他组更多。未检测到其他明确差异。棉絮斑似乎是视网膜受到各种损伤后的常见表现，很可能起源于血管阻塞。
