Kyiv Clinical Ophthalmology Hospital Eye Microsurgery Center, Medical City, Kyiv, Ukraine.
Stein Eye Institute, University of California, California, Los Angeles, USA.
Curr Eye Res. 2021 Dec;46(12):1832-1843. doi: 10.1080/02713683.2021.1933056. Epub 2021 Jul 26.
To analyze the accuracy of 18 intraocular lens (IOL) power calculation formulas in eyes with axial length (AL) ≤ 22 mm.
We analyzed 241 eyes of 241 patients. Eighteen formulas were evaluated: Barrett Universal II (BUII), EVO 2.0, Haigis, Hoffer Q, Holladay 1 and 2, Cooke K6, Kane, LadasSuperFormula AI, Naeser 2, Olsen, Panacea, Pearl-DGS, RBF 2.0, SRK/T, T2, VRF and VRF-G. Optical biometry was performed with an IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany). With lens constants optimized for the whole range of AL, the mean prediction error (PE) and its standard deviation (SD), the median absolute error (MedAE), the mean absolute error (MAE) and the percentage of eyes with PEs within ±0.25 D, ±0.50 D and <±1.00 D were calculated.
Post-hoc analysis of the absolute PE revealed statistically significant differences ( < .05) between some of the newer formulas (K6, Kane, Naeser 2, Olsen and VRF-G), which obtained the lowest MedAE (respectively, 0.308, 0.300, 0.277, 0.310 and 0.276 D) and the remaining ones. These formulas yielded also the highest percentage of eyes with a PE within ±0.50 D (70.54%, 72.20%, 71.37%, 70.95% and 73.03%, respectively), whereas Panacea and SRK/T yielded the lowest percentage (62.24%), with a stastically significant difference ( < .05) with respect to most formulas.
In eyes with AL ≤22.0 mm, new formulas (K6, Kane, Naeser 2, Olsen and VRF-G) offer the most accurate predictions of postoperative refraction.
分析轴向长度（AL）≤22mm 的眼的 18 种人工晶状体（IOL）计算公式的准确性。
我们分析了 241 例 241 只眼。评估了 18 种公式：Barrett Universal II（BUII）、EVO 2.0、Haigis、Hoffer Q、Holladay 1 和 2、Cooke K6、Kane、LadasSuperFormula AI、Naeser 2、Olsen、Panacea、Pearl-DGS、RBF 2.0、SRK/T、T2、VRF 和 VRF-G。使用 IOLMaster 700（德国卡尔蔡司公司）进行光学生物测量。使用优化了整个 AL 范围的镜片常数，计算了平均预测误差（PE）及其标准差（SD）、中位数绝对误差（MedAE）、平均绝对误差（MAE）以及预测误差在±0.25D、±0.50D 和 <±1.00D 范围内的眼的百分比。
绝对 PE 的事后分析显示，一些较新的公式（K6、Kane、Naeser 2、Olsen 和 VRF-G）之间存在统计学上的显著差异（<0.05），这些公式获得了最低的 MedAE（分别为 0.308、0.300、0.277、0.310 和 0.276D）和其余公式。这些公式还产生了预测误差在±0.50D 范围内的眼的百分比最高（分别为 70.54%、72.20%、71.37%、70.95%和 73.03%），而 Panacea 和 SRK/T 的百分比最低（62.24%），与大多数公式相比具有统计学显著差异（<0.05）。
在轴向长度≤22.0mm 的眼中，新公式（K6、Kane、Naeser 2、Olsen 和 VRF-G）对术后屈光的预测最为准确。
