Samson S, Zatorre R J
Montreal Neurological Institute, Quebec, Canada.
Brain Cogn. 1988 Jun;7(3):348-60. doi: 10.1016/0278-2626(88)90008-5.
Seventy-seven subjects who had undergone unilateral temporal, frontal, or frontotemporal lobectomy for the relief of focal epilepsy as well as a group of 20 normal control subjects were tested in two discrimination tasks, requiring the detection of a single-note change in a pattern of three notes played either successively or simultaneously. Patients with right temporal and right frontotemporal excisions demonstrated a significant deficit in melodic discrimination in comparison to the normal control subjects. Further analysis showed that left-temporal lobectomy including excision of Heschl's gyri (the primary auditory receiving area) led to a significant impairment as well, whereas anterior left temporal-lobe damage did not result in a significant deficit. The results suggest that melodic discrimination depends largely but not exclusively on the right temporal lobe, and that the left Heschl's gyri also seem to be necessary to succeed in this task. In the harmonic task, the differences between the groups did not reach significance, although the two tasks were highly correlated.
77名因缓解局灶性癫痫而接受单侧颞叶、额叶或额颞叶切除术的受试者以及20名正常对照受试者参与了两项辨别任务测试，任务要求检测在依次或同时播放的三个音符模式中单个音符的变化。与正常对照受试者相比，接受右侧颞叶和右侧额颞叶切除术的患者在旋律辨别方面表现出明显缺陷。进一步分析表明，包括切除颞横回（主要听觉接收区域）的左侧颞叶切除术也导致了显著损伤，而左侧颞叶前部损伤并未导致显著缺陷。结果表明，旋律辨别在很大程度上但并非完全依赖于右侧颞叶，并且左侧颞横回似乎对于完成这项任务也是必要的。在和声任务中，尽管两项任务高度相关，但各组之间的差异未达到显著水平。
