Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming 650091, P. R. China.
Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming 650091, P. R. China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China.
J Hazard Mater. 2021 Sep 5;417:126074. doi: 10.1016/j.jhazmat.2021.126074. Epub 2021 May 11.
Microwavable plastic food containers (MPFCs) are extensively used for food storage, cooking, rapid heating and as take-out containers. There is an urgent need to investigate whether MPFCs pose potential health risks, as a result of the migration of chemicals into foods. Herein, 42 intentionally added substances (IAS) and > 100 non-IAS (NIAS) migrating from MPFCs were identified in food simulants according to Regulation (EU). The migration of major IAS and NIAS was higher in 95% ethanol compared to other simulants, and gradually decreased following repeated use. NIAS, including Cramer class III toxic compounds, such as PEG oligomers of N,N-bis(2-hydroxyethyl) alkyl(C8-C18)amines, isomers of hexadecanamide and oleamide, and Irgafos 168 OXO were detected and exceeded the recommended limits in some MPFCs. Furthermore, microplastics (MPs) were detected with high values of over one million particles/L in some MPFCs in a single test, and migration behaviors of MPs in different MPFCs were diverse. Surprisingly, this rigorous migration might result in an annual intake of IAS/NIAS up to 55.15 mg and 150 million MPs particles if take-out food was consumed once a day. Multi-safety evaluation studies on the migration of various chemicals from MPFCs to foodstuffs during food preparation should be assessed.
微波塑料食品容器（MPFCs）广泛用于食品储存、烹饪、快速加热和外卖容器。由于化学物质迁移到食品中，因此迫切需要研究 MPFC 是否会带来潜在的健康风险。在此，根据法规（EU），在食品模拟物中鉴定出了 42 种有意添加的物质（IAS）和 >100 种非 IAS（NIAS）。与其他模拟物相比，95%乙醇中主要 IAS 和 NIAS 的迁移率更高，并且随着重复使用逐渐降低。NIAS，包括 Cramer 类 III 毒性化合物，如 N,N-双（2-羟乙基）烷基（C8-C18）胺的聚乙二醇低聚物、己酰胺和油酰胺的异构体，以及 Irgafos 168 OXO，在一些 MPFC 中被检测到并超过了建议的限量。此外，在单次测试中，一些 MPFC 中检测到的 MPs 值高达上百万个/升以上，不同 MPFC 中 MPs 的迁移行为也存在差异。令人惊讶的是，如果每天吃一次外卖食品，这严格的迁移可能导致每年摄入 IAS/NIAS 高达 55.15 毫克和 1.5 亿个 MPs 颗粒。在食品制备过程中，应评估从 MPFC 到食品中各种化学物质迁移的多安全评估研究。
