Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.
Department of Ophthalmology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.
Graefes Arch Clin Exp Ophthalmol. 2020 Jan;258(1):137-146. doi: 10.1007/s00417-019-04482-0. Epub 2019 Oct 20.
This study was performed to compare anterior ocular biometric measurements of deep-range swept-source anterior segment optical coherence tomography (AS-OCT) (CASIA2) versus short-range swept-source AS-OCT (CASIA SS-1000), ultrasonography (AL-4000), and Scheimpflug camera analysis (Pentacam and EAS-1000) in patients with cataract.
One hundred eighty-five eyes of 128 participants with mild refractive error or cataract were examined. The central corneal thickness (CCT), aqueous depth (AQD), and lens thickness were obtained. The repeatability of CASIA2 measurements was assessed.
In patients with cataract, the CCT, AQD, lens thickness, and lens anterior curvature by CASIA2 showed high intraclass correlation coefficients (ICCs) of > 0.99. Conversely, measurements of the posterior part of the lens such as lens posterior curvature showed lower ICCs. The ICCs were higher in healthy young participants than in patients with cataract. The ICCs tended to be lower in patients with mild than dense cataract. There was no statistically significant difference in the CCT and AQD between the CASIA2 and CASIA SS-1000 or in the lens thickness measurements between the CASIA2 and AL-4000 and between the CASIA2 and EAS-1000. There was a significant linear correlation in the biometric measurements between the CASIA2 and the other instruments.
We evaluated the biometric measurements of the anterior eye segment by the CASIA2. The CASIA2 yielded results comparable with those of the CASIA SS-1000, ultrasonography, and Scheimpflug camera. However, mild cataract decreased the repeatability of measurements of the posterior part of the lens.
本研究旨在比较深度扫描源眼前节光学相干断层扫描（AS-OCT）（CASIA2）与短程扫描源 AS-OCT（CASIA SS-1000）、超声（AL-4000）和Scheimpflug 相机分析（Pentacam 和 EAS-1000）在白内障患者眼前节生物测量中的差异。
对 128 名轻度屈光不正或白内障患者的 185 只眼进行检查。测量中央角膜厚度（CCT）、房水深度（AQD）和晶状体厚度。评估了 CASIA2 测量的重复性。
在白内障患者中，CASIA2 的 CCT、AQD、晶状体厚度和晶状体前曲率的测量值具有 >0.99 的高组内相关系数（ICC）。相反，晶状体后表面的测量值如晶状体后曲率的 ICC 较低。健康年轻参与者的 ICC 高于白内障患者。白内障患者中，晶状体混浊程度较轻的 ICC 较低。CASIA2 与 CASIA SS-1000 之间的 CCT 和 AQD 测量值、CASIA2 与 AL-4000 之间的晶状体厚度测量值以及 CASIA2 与 EAS-1000 之间的晶状体厚度测量值之间无统计学差异。CASIA2 与其他仪器的生物测量值之间存在显著的线性相关性。
我们评估了 CASIA2 对眼前节的生物测量值。CASIA2 的结果与 CASIA SS-1000、超声和 Scheimpflug 相机相当。然而，轻度白内障降低了晶状体后表面测量的重复性。
