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蒙古药食同源植物化学成分的生物活性评价及其在防治人畜传染病和解决健康问题中的应用。

Biological activity evaluations of chemical constituents derived from Mongolian medicinal forage plants and their applications in combating infectious diseases and addressing health problems in humans and livestock.

机构信息

Division of Pharmacognosy, Tohoku Medical and Pharmaceutical University, 4-1 Komatsushima 4-chome, Aoba-ku, Sendai, 981-8558, Japan.

School of Engineering and Applied Sciences, National University of Mongolia, POB-617/46A, Ulaanbaatar, 14201, Mongolia.

出版信息

J Nat Med. 2021 Sep;75(4):729-740. doi: 10.1007/s11418-021-01529-7. Epub 2021 May 21.

Abstract

Mongolian nomadic people possess traditional knowledge of wild plants that grow in their areas of habitation. Many of these are forage plants in nature and are consumed by livestock. However, these plants are known to have medicinal and/or toxic properties. To establish a scientific understanding of the plants, and in turn, offer sound knowledge on their applications and effective use, it is essential to collect data pertaining to the chemical constituents of each plant. Therefore, the first objective of this study was to identify and determine the structural constituents of the forage plants that were available to our research group. Furthermore, in an attempt to demonstrate the biological activities of the isolated chemical compounds, we focused on solving some of the social issues affecting Mongolian communities, including protozoan diseases affecting livestock, vectors of infectious diseases, and the general health of humans and their livestock. The results of the chemical constituents derived from Mongolian medicinal plants and their biological activities that were studied in the recent decade are also described herein.

摘要

蒙古游牧民族拥有其居住地野生植物的传统知识。这些植物中有许多是自然界中的饲料植物,被牲畜食用。然而,这些植物具有药用和/或毒性。为了建立对植物的科学认识,并相应地提供有关其应用和有效使用的可靠知识,收集与每种植物的化学成分有关的数据是必不可少的。因此,本研究的第一个目标是鉴定和确定我们研究小组可获得的饲料植物的结构成分。此外,为了展示分离出的化学化合物的生物活性,我们专注于解决一些影响蒙古社区的社会问题,包括影响牲畜的原生动物病、传染病的媒介物以及人类及其牲畜的一般健康状况。本文还描述了最近十年从蒙古药用植物中提取的化学成分及其生物活性的研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26bc/8397696/68a418965c63/11418_2021_1529_Fig1_HTML.jpg

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