Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Chest. 2021 Apr;159(4):e197-e201. doi: 10.1016/j.chest.2020.11.044. Epub 2021 Apr 6.
A 27-year-old man was hospitalized in the burn unit after sustaining an acute inhalational injury and facial burns after an accidental occupational exposure to an industrial disinfectant consisting of a mixture of hydrogen peroxide (15%-30%), acetic acid (5%-15%), and peracetic acid (5%-15%). He demonstrated cough, shortness of breath, and hoarseness of voice at presentation that had developed 6 h after exposure. In addition to the inhalational injury of the vocal cords and lower airways on bronchoscopy (Fig 1), the patient also was diagnosed with acute inhalational pneumonitis based on the findings of hypoxemic respiratory failure and bilateral perihilar airspace opacities on chest radiography (Fig 2). He required intubation and mechanical ventilation initially for 2 days for upper airway edema and was discharged 19 days after exposure with resolution of hypoxemia and reduction of airspace opacities on chest radiography. However, symptoms of productive cough and shortness of breath on exertion persisted, and he was rehospitalized 27 days after exposure. He was a nonsmoker with no prior history of atopy, asthma, or lung disease. His medical history was remarkable for hypertension and severe obesity with a BMI of 34.7 kg/m.
一名 27 岁男性在职业暴露于一种由过氧化氢(15%-30%)、乙酸(5%-15%)和过氧乙酸(5%-15%)混合而成的工业消毒剂后,出现急性吸入性损伤和面部烧伤,被收入烧伤科住院治疗。他在接触后 6 小时出现咳嗽、呼吸急促和声音嘶哑。除了支气管镜检查显示声带和下呼吸道的吸入性损伤(图 1)外,根据低氧性呼吸衰竭和胸部 X 线显示双侧肺门周围气腔混浊的结果,该患者还被诊断为急性吸入性肺炎(图 2)。他最初因上呼吸道水肿需要插管和机械通气 2 天,接触后 19 天出院,低氧血症和胸部 X 线气腔混浊减轻。然而,他仍持续出现有痰的咳嗽和活动时呼吸急促的症状,在接触后 27 天再次住院。他不吸烟,无特应性、哮喘或肺部疾病史。他的病史有高血压和严重肥胖,BMI 为 34.7kg/m²。