Wang Mengge, He Guanglin, Gao Shuang, Jia Fuquan, Zou Xing, Liu Jing, Wang Shouyu, Ye Ziwei, Hou Yiping, Wang Zheng
Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Sciences, Ministry of Justice, Shanghai 200063, China; Institute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Institute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, China; Department of Anthropology and Ethnology, Institute of Anthropology, National Institute for Data Science in Health and Medicine, and School of Life Sciences, Xiamen University, Xiamen 361005, China.
Genomics. 2021 Jul;113(4):2199-2210. doi: 10.1016/j.ygeno.2021.05.010. Epub 2021 May 19.
The Mongolians are mainly distributed in the modern state of Mongolia, China, Russia, and other countries. While the historic and archaeological records of the rise and fall of the Mongol Empire are well documented, little has been known about the genetic legacy of modern Mongolian populations. Here, 611 Mongolian individuals from Hohhot, Hulunbuir, and Ordos of China were genotyped via the 47 Insertion/Deletion markers. Forensically statistical parameters indicated that this InDel system could be applied to forensic investigation in Mongolian populations. The comprehensive population comparisons indicated that targeted Mongolian populations are a homogeneous population, which kept close genetic proximity with geographically northern East Asians. The findings of the model-based clustering analysis revealed a southern East Asian-specific ancestral component, which was maximized in Hainan Li, and Mongolian populations harbored relatively less Hainan Li-related ancestry and more northern East Asian-related ancestry compared with reference Tai-Kadai, Austroasiatic and Sinitic people.
蒙古族主要分布在现代的蒙古国、中国、俄罗斯及其他国家。虽然蒙古帝国兴衰的历史和考古记录有详尽记载，但对于现代蒙古族人群的基因遗产却知之甚少。在此，对来自中国呼和浩特、呼伦贝尔和鄂尔多斯的611名蒙古族个体通过47个插入/缺失标记进行了基因分型。法医学统计参数表明，该插入缺失系统可应用于蒙古族人群的法医调查。全面的人群比较表明，目标蒙古族人群是一个同质化群体，与地理上的东亚北部人群保持着密切的基因亲缘关系。基于模型的聚类分析结果揭示了一个东亚南部特有的祖先成分，在海南黎族中最为显著，与作为参照的侗台语族、南亚语系和汉藏语系人群相比，蒙古族人群拥有相对较少的与海南黎族相关的祖先成分和较多的与东亚北部相关的祖先成分。
