Department of Infectious Diseases and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, TR-34093 Istanbul, Turkey.
Gastroenterol Clin North Am. 2021 Jun;50(2):341-360. doi: 10.1016/j.gtc.2021.02.004.
Gastrointestinal (GI) tuberculosis (TB) remains a significant problem worldwide, and may involve the luminal GI tract from oral cavity to perianal area in addition to associated viscera and peritoneum. Although GI TB more commonly affects immunocompromised hosts, it can also occur in immunocompetent people. Diagnosis is difficult because it usually mimics a malignancy or inflammatory bowel disease. A high index of clinical suspicion and appropriate use of combined investigative methods help in early diagnosis, and reduce morbidity and mortality. Anti-TB therapy is the same as for pulmonary disease, and invasive and specialized interventions are reserved for selected complications.
胃肠道(GI)结核病(TB)仍然是一个全球性的重大问题,除了相关的内脏和腹膜外,它还可能涉及从口腔到肛门周围的腔道 GI tract。尽管 GI TB 更常影响免疫功能低下的宿主,但它也可能发生在免疫功能正常的人身上。诊断很困难,因为它通常模仿恶性肿瘤或炎症性肠病。高临床怀疑指数和适当使用联合研究方法有助于早期诊断,并降低发病率和死亡率。抗结核治疗与肺部疾病相同,侵入性和专门干预措施仅保留给选定的并发症。